Results 201 to 210 of about 374,767 (358)

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen   +4 more
wiley   +1 more source

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats. [PDF]

open access: yesJ Appl Toxicol
Freire CGF   +9 more
europepmc   +1 more source

Sacubitril/Valsartan Ameliorates Inflammation and Oxidative Stress in Hypertensive Heart Disease by Upregulating CAMKK2 Protein and Modulating the AMPK/AKT/GSK‐3β Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley   +1 more source

Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia

open access: yesMovement Disorders, EarlyView.
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi   +6 more
wiley   +1 more source

Polyethylene microplastics disrupt renal function, mitochondrial bioenergetics, redox homeostasis, and histoarchitecture in Wistar rats. [PDF]

open access: yesSci Rep
Kehinde SA   +8 more
europepmc   +1 more source

Protective Roles of Prebiotics and Probiotics Against Environmental Pollutant‐Induced Toxicities: A Systematic Review of Animal Studies

open access: yesMolecular Nutrition &Food Research, EarlyView.
Pollutant‐induced epithelial damage also leads to a cascade of harmful effects, including reduced mucus secretion, decreased luminal pH, and enhanced absorption of toxins. These changes contribute to oxidative stress (↑ malondialdehyde (MDA); ↓ superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and heightened ...
Meysam Zarezadeh Ph.D.   +5 more
wiley   +1 more source

Histone acetylation of the htr3a gene in the prefrontal cortex of Wistar rats regulates ethanol-seeking behavior.

open access: green, 2012
Yahui Xu   +6 more
openalex   +1 more source

Effect of Electromagnetic Field Radiation at 2300 MHz on Wistar Rats

open access: hybrid, 2020
Bhushanam Kasukurthi   +6 more
openalex   +1 more source

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