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Acetaminophen nephrotoxicity in male Wistar rats
Archives of Toxicology, 1992Acute acetaminophen (APAP) nephrotoxicity was studied in male Wistar rats 1 h after different APAP single doses (200, 500 and 1000 mg/kg body wt, i.p.). Significant impairments in glomerular filtration rate (GFR) and clearance of p-aminohippuric acid (ClPAH) were observed in a dose-dependent way, although tubular parameters measured, water and ...
María Mónica Elías +2 more
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Induced palatal candidosis in the Wistar rat
Archives of Oral Biology, 1981Palatal candidosis was induced by inoculating Candida albicans 3091 (serotype A) under an acrylic appliance. After 1 week, the palatal epithelium showed acute inflammatory cell infiltration and surface colonization by blastospores. Two weeks after inoculation, the inflammation had increased, micro-abscesses were observed and fungal hyphae penetrated ...
B.S. Shakir, M.V. Martin, C.J. Smith
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A supernumerary forelimb in a Wistar rat
Laboratory Animals, 1987A fifth limb, quite independent of the others, was found in a pup born in our colony of Wistar rats. The malformation is described.
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The fate of oxalic acid in the Wistar rat
Xenobiotica, 19811. An established procedure for determining oxalate in human urine has been modified for rat urine. The daily excretion of oxalate by the male Wistar rat is 570-650 microgram. 2. Oxalate excretion in rat urine following i.p. administration of [14C]oxalic acid (1-70 mg/kg) has been studied. The rate and degree of excretion are dose-dependent. 3.
Penny Gadiel +2 more
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Hepatotoxicity of graphene oxide in Wistar rats
Environmental Science and Pollution Research, 2020Graphene oxide (GO) has a multitude of applications in areas of nanomedicine, electronics, textile, water purification, and catalysis among others. GO is relatively easier to manufacture and customize as compared with other carbon-based nanomaterials.
Naresh K. Nirmal +2 more
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Resistance to mineralocorticoids in Wistar-Furth rats
American Journal of Physiology-Heart and Circulatory Physiology, 1997Wistar-Furth rats (WF) do not develop hypertension when treated with salt and mineralocorticoids and therefore may be useful for investigating the mechanisms of mineralocorticoid action and hypertension. In the present studies, we determined vascular and renal responses of WF to mineralocorticoids. Control Wistar rats (W) developed deoxycorticosterone
Muhammad M. Islam +5 more
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Transplantation of the Interfrontal Suture in the Wistar Rat
Cells Tissues Organs, 1982By excising a 3-day-old interfrontal suture with adnexa and transplanting it into the sagittal suture of a 10-week-old rat of the same inbred strain, the development of the interfrontal suture under experimental conditions could be studied. The effect was a distinct delay of the moment of closure of the suture, namely, from normal period of 1 week to ...
H.A.J. Oudhof, I.S. Markens
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Polymorphism in Diazepam Metabolism in Wistar Rats
Journal of Pharmaceutical Sciences, 2004We observed variations in the metabolism of diazepam in Wistar rats. We studied these variations carefully, and found that the variations are dimorphic and about 17% of male rats of Wistar strain we examined showed two times higher diazepam metabolic activities in their liver microsomes than the rest of animals at the substrate concentrations less than
Konomu Saito +5 more
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Tumor-Induced Anorexia in the Wistar Rat
Science, 1981The transplantable Leydig cell tumor of Wistar rats, LTW(m), caused decreased food consumption and weight loss in the host within 2 weeks of implantation. The tumor was small, did not metastasize, and did not affect several parameters of biochemical function.
John P. Mordes, Aldo A. Rossini
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A revaluation of the haemoglobin electrophoretogram of the wistar rat
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971Abstract 1. 1. Haemoglobins of Wistar rats have been examined by starch and polyacrylamide gel electrophoresis 2. 2. Two haemoglobins are produced during yolk sac erythropoiesis, and two additional haemoglobins appear during liver erythropoiesis. 3. 3. All four haemoglobins persist in the adult. 4. 4.
Norman Maclean, Andrew R.E. Shaw
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