Results 301 to 310 of about 1,615,506 (361)
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Endocardial Schwannomas in the Wistar Rat
Journal of Veterinary Medicine Series A, 2005SummaryEndocardial neoplasms were observed in 13 Wistar rats, 15–30 months old, from a 30‐month inhalation study. Eight of the rats were dissected at 30 months and the other five between 15 and 29 months. Histologically, the lesions in the heart were diagnosed as endocardial schwannomas.
A, Teredesai, T, Wöhrmann
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Genotoxicity of nimesulide in Wistar rats
Drug and Chemical Toxicology, 2013It is mandatory for all new drugs to be tested for their potential genotoxicity in addition to general toxicity testing. Some old drugs have not been tested adequately for their genotoxic effects because these were in use before the local regulations were enforced. According to the material safety database, the toxicological effect of nimesulide is not
Debojyoti, Borkotoky +3 more
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Pharmacognosy Research, 2017
Background: The number of individuals with diabetes is increasing daily, and diabetes is presently estimated to affect about 422 million adults worldwide.
Elizabeth I Omodanisi +3 more
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Background: The number of individuals with diabetes is increasing daily, and diabetes is presently estimated to affect about 422 million adults worldwide.
Elizabeth I Omodanisi +3 more
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METABOLISM OF MYOSMINE IN WISTAR RATS
Drug Metabolism and Disposition, 2005The alkaloid myosmine is present not only in tobacco products but also in various foods. Myosmine is easily nitrosated, yielding 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and the esophageal tobacco carcinogen N'-nitrosonornicotine. Due to its widespread occurrence, investigations on the metabolism and activation of myosmine are needed for risk ...
Wolfgang, Zwickenpflug +2 more
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Lymphoproliferative lesions in BB Wistar rats
Metabolism, 1983Fifteen percent of long-term diabetic BB Wistar rats developed abdominal B cell lymphoproliferative lesions which ranged from minute mesenteric aggregates of plasma cells and lymphocytes to malignant lymphoma with features of immunoblastic sarcoma or plasma-cell lymphoma.
T A, Seemayer +3 more
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Lipids, 1976
AbstractThe bile acid pool was found to be ca. 50 μmoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 μmoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration ...
M M, Fisher, G, Kakis, I M, Yousef
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AbstractThe bile acid pool was found to be ca. 50 μmoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 μmoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration ...
M M, Fisher, G, Kakis, I M, Yousef
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Sleeve Gastrectomy Model in Wistar Rats
Obesity Surgery, 2007Sleeve gastrectomy (SG) has been used for the surgical treatment of morbid obesity, as a first step or as a definitive treatment. The objective of this pilot study was to establish an animal model for SG in Wistar rats.12 male Wistar rats were operated on.
João, de Bona Castelan +6 more
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Retinal dystrophy in Wistar-Furth rats
Experimental Eye Research, 1988A form of retinal degeneration in the Wistar-Furth strain of rat is described. The changes observed was classified as either mild or severe, depending on the severity of the dystrophy seen by light and electron microscopy. In the mild stage, there was a slight decrease in the number of photoreceptor nuclei in the outer nuclear layer (ONL) and there ...
W L, Lin, E, Essner
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Spontaneous Neoplasms in Control Wistar Rats
Toxicological Sciences, 1994Neoplastic data on 1370 control Wistar rats from 10 carcinogenicity bioassays done between 1980 and 1990 were reviewed. Mean percentage survival at 104 weeks was 58% for males and 59% for females. A total of 1857 neoplasms were diagnosed in 466 (68%) male and 582 (85%) female rats; 1390 were benign and 467 were malignant (12% with metastasis).
K M, Walsh, J, Poteracki
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