Results 51 to 60 of about 168,253 (297)
TPP‐SAT, a mitochondria‐targeted natural enzyme‐cascade nanogel, selectively scavenges mitochondrial ROS (e.g., H2O2/·O2⁻) and converts them into therapeutic O2 via enzymatic cascades, alleviating hypoxia and inflammation. It rebalances M1/M2 macrophage polarization, activates the Nrf2 pathway while suppressing NF‐κB, enhances antioxidant defenses, and
Yanfen Zheng+6 more
wiley +1 more source
Trichosomoides crassicauda infection in wistar rats
Laboratory animals, including rats, play an important role in biomedical research and advances. The human care and management of these animals is an ongoing concern.
Bahrami, S., +2 more
doaj
Estudo do efeito de dreno de penrose na cavidade peritoneal de ratos
OBJETIVO: Estudar o efeito do dreno de Penrose na cavidade peritoneal de ratos. MÉTODO: Foram selecionados 30 ratos Wistar do mesmo sexo,divididos em três grupos de 10 animais, todos submetidos à introdução e fixação de dreno (Penrose) na cavidade ...
Gutemberg Fernandes de Araújo+4 more
doaj +1 more source
Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan+13 more
wiley +1 more source
Wistar rats were used: 15-16 and 20-21 diurnal embryos, newborns, 2.5 and 5, 7.5 and 10, 15, 20, 25, 30, 35, 40 and 45 day-old rats. From compact and trabecular layers of the myocardium of rats of different ages, ultrafine sections were prepared.
Zahoruiko G. E.+2 more
doaj +1 more source
Cluster‐assembled nanocomposite devices are employed for the classification of neuronal traces, without any preprocessing of the input time‐series or prior training of the nonlinear devices. The classification method relies on the statistical analysis of the device's output time‐series, achieving higher classification accuracy compared to more energy ...
Filippo Profumo+5 more
wiley +1 more source
Animal models of cisplatin‐induced neuropathic pain
This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li+9 more
wiley +1 more source
OBJETIVO: Comparar a lesão hepatocelular ocasionada pelo emprego do pré-condicionamento isquêmico e de duas outras modalidades de clampeamento tríade portal: clampeamento contínuo e intermitente.
Fábio Neves da Silva+2 more
doaj +1 more source
Influence of nifedipine on gingiva of Wistar rats
Noninflammatory hyperplastic growth of gingiva induced by calcium channel blockers, mostly nifedipine, is often seen in everyday dental practice. In order to establish an association of nifedipine and gingival hyperplasia, experimental model was used. Wistar rats were given water solution of nifedipine in different daily doses, using specially designed
openaire +4 more sources
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang+7 more
wiley +1 more source