Results 51 to 60 of about 3,729,500 (327)

Inestigation on withdrawal strength and moment resistance of mortise and tenon joint [PDF]

open access: yesتحقیقات علوم چوب و کاغذ ایران, 2009
The influence withdrawal strength and bending moment of mortise and tenon joint is investigated. Based on vast application of this type of different length of joint, the effect of tenon lengths (20 , 30, 40, mm) and wood type (beech, alder,spruce) These ...
amir lashgari, Ahmad Jahan latibari
doaj   +1 more source

Medical education and law: withholding/withdrawing treatment from adults without capacity

open access: yesInternal Medicine Journal, 2015
AbstractBackgroundLaw is increasingly involved in clinical practice, particularly at the end of life, but undergraduate and postgraduate education in this area remains unsystematic. We hypothesised that attitudes to and knowledge of the law governing withholding/withdrawing life‐sustaining treatment from adults without capacity (the WWLST law) would ...
Parker, M   +4 more
openaire   +3 more sources

State Failure, Crisis of Governance and Disengagement from the State in Africa [PDF]

open access: yes, 2009
This paper examines the phenomenon of citizen's disengagement from the state in Africa in the post-colonial era. The paper observes that the declining capacity of the state for social provisioning provides the context for citizens' withdrawal from the ...
Mojeed Adekunle Animashaun
core  

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser   +5 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The influence of moisture content variation on the withdrawal capacity of self-tapping screws [PDF]

open access: yes, 2014
Due to high axial load-bearing capacity and economical application without pre-drilling, self-tapping screws are widely used in modern timber constructions nowadays.
Branco, Jorge M.   +4 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Water Scarcity in the Zambezi Basin in the Long-Term Future: A Risk Assessment [PDF]

open access: yes, 2003
The aim of this paper is to explore possible futures for the Zambezi basin and to estimate the risks of different water management strategies. Existing uncertainties are translated into alternative assumptions.
Hoekstra, Arjen Y.
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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