Results 201 to 210 of about 84,365 (267)

The contingency effects of abusive supervision of coworker on helping behaviors: the relationships among the perpetrator, the victim, and the third party. [PDF]

Front Psychol
Sun M, Luo LT, Zhao DN.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Patterns and implications of 2025 NIH-F31 grant terminations for the predoctoral training pipeline. [PDF]

Health Aff Sch
Jaramillo J, Harkness A.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The health consequences of politically-induced trauma. [PDF]

PLOS Ment Health
Horwitz RI.
europepmc   +1 more source

A minyan. [PDF]

Palliat Support Care
Breitbart W.
europepmc   +1 more source

Copper Replacement: A Life-Saving Treatment. [PDF]

Cureus
Patel AJ.
europepmc   +1 more source

Cross-platform certification of the qubit space with a minimal number of parameters. [PDF]

Sci Rep
Rybotycki T, Białecki T, Batle J, Tworzydło J, Bednorz A.   +4 more
europepmc   +1 more source

Acute Hemolytic Anemia Due to Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Triggered by Helicobacter pylori Quadruple Therapy in a Jehovah's Witness: A Case Report. [PDF]

Cureus
Dhami AS, Koladiya P, Sahhar F.
europepmc   +1 more source