Results 71 to 80 of about 641,784 (306)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: To evaluate the risk factors of prolonged hospitalization in patients with hyperemesis gravidarum (HEG). Material and Methods: The medical records of 114 patients who were admitted to the Zekai Tahir Burak Womens Health Education and Research ...
Hasan Onur Topcu, Can Tekin iskender, Asli Oskovi, Hakan Timur, Korkut Daglar, Nuri Danisman   +5 more
doaj  

Cost‐effectiveness of interventions for screening and management of sickle cell disease during pregnancy: A systematic review

Pregnancy
Background Sickle cell disease (SCD) is a widespread inherited condition that has increased in global prevalence by 41% since 2000. Despite advancements in understanding the pathophysiology and clinical management of SCD, limited evidence exists ...
Jenny Jung, Samia Aziz, Maureen Makama, Nick Scott, Katherine E. Eddy, Joshua F. Ginnane, Joshua P. Vogel   +6 more
doaj   +1 more source

“Three-Step Approach” Versus “See-and-Treat Procedure” in women with “High Grade Squamous Intraepithelial Lesion” (HSIL) or “Atypical Squamous Cells cannot exclude HSIL” (ASC-H) Cytology

Gynecology Obstetrics & Reproductive Medicine, 2018
Objective: The purpose of this study was to examine the correlation between histological findings in women with HSIL or ASC-H who have undergone loop electrosurgical excisional procedure with “Three-Step Approach” and “See-and-Treat Procedure".
Mustafa Erkan Sari, Ibrahim Yalcin, Hanifi Sahin, Mehmet Mutlu Meydanli, Tayfun Gungor   +4 more
doaj   +1 more source

Age Differences in Women's Perceptions of Their Health Problems and Concerns [PDF]

This paper addresses age differences in women's perceptions of their health problems and concerns. The data are drawn from interviews with a stratified random sample of 356 women in Hamilton, Canada.
Margaret Denton, Vivienne Walters
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Maternal Near Miss Morbidity and Maternal Mortality in a Tertiary Referral Center in Turkey

Gynecology Obstetrics & Reproductive Medicine, 2017
Objective: The objective of the study is to present the maternal near miss and maternal mortality cases from a tertiary hospital and to evaluate the factors associated with the presence of maternal near miss.
Dilek Uygur, Yaprak Engin Üstün, Özgür Kara, Kudret Erkenekli, Selcen Yüksel, Salim Erkaya, Sema Sanisoğlu, Nuri Danışman, Aykan Yücel   +8 more
doaj   +1 more source

Ethnolinguistic concordance and the receipt of postpartum IUD counseling services in Sri Lanka. [PDF]

, 2018
CONTEXT: Ethnic and linguistic concordance are important dimensions of the patient-physician relationship, and are linked to health care disparities.
Canning, David, de Silva, Ranjith, Karra, Mahesh, Pearson, Erin, Samarasekera, Arnjali, Shah, Iqbal   +5 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source