Results 51 to 60 of about 7,975,658 (293)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Where’s My Queer BBQ?: Supporting Queer Students at Historically Women’s Colleges [PDF]
, 2018 The experiences of Queer students at institutions of higher education have long been the subject of scholarship. Scholars explored research on campus climate, experience, and identity development.
Dews, Sarah D.
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A brief history of women’s history [PDF]
, 2016 “Where are the women?” When Cynthia Enloe posed this question in 1989, she was thinking about the world of international politics. But the question has also been a driving force for a number of historians who have sought to move beyond the narratives of “
Bourbonnais, Nicole
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
‘The imagination is largely the child of the flesh’: Virginia Woolf’s Embodied Historicity
Études Britanniques Contemporaines‘Memories of a Working Women’s Guild’ (1930, rev. 1931) stands apart in Virginia Woolf’s profuse essayistic production. Part political essay and personal reminiscing, part sociological reflection and meta-historical exploration, it should be read as one ...
Catherine Bernard
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Études Écossaises, 2013 Over the last two decades, research on women and gender in Scotland has flourished and we have an increasingly full picture of women’s lives at all social levels across the medieval to modern periods.
Katie Barclay, Rosalind Carr
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source