Results 51 to 60 of about 127,046 (222)

USSR Policy on Communist Education and Promotion of Women of the East to Leadership Positions: Exemplified by the Uzbek SSR

RUDN Journal of Russian History
The author analyzes the reforms implemented by the Communist Party of the Uzbek SSR through its propaganda and political education departments to increase women’s socio-political activity.
Nodira S. Rasulova
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Dekonstruksi Narasi Sejarah Perempuan dari Perspektif Kritis Guru Sejarah

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
History education is a strategic instrument for politics and ideological indoctrination. This tendency creates the dominance of the grand narrative in historical education, leading to injustice toward women.
Aulia Novemy Dhita, Nana Supriatna, Didin Saripudin, Erlina Wiyanarti   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

La querelle des femmes

Lychnos, 2017
In the article ”Revisiter la querelle des femmes. Mais de quoi parle-t-on?” the literary historian Éliane Viennot posed a question that has troubled scholars of European women’s history: what do we mean by the term la querelle des femmes? Even though la
Matilda Amundsen Bergström
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Contexte de gen: Roluri, drepturi şi mişcări ale femeilor din România la sfârşitul secolului al XIX-lea şi la începutul secolului al XX-lea

Sociologie Românească, 2014
This article functions as a gender context for women’s participation, work and contribution to some of the sociological research and social interventions during the 1920s and the 1930s in Romania.
Theodora-Eliza Văcărescu
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Wonders and Politics of the Chosŏn Dynasty: Reflections on the Unexplored Side of the Chosŏn Neo-Confucian System

Religions
Wonder was deeply rooted in the Chosŏn Neo-Confucian system. Through this wonder, we can see various layers of consciousness of Neo-Confucian scholars.
Jonghyun Na
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source