Results 201 to 210 of about 5,204,119 (249)

Women's social care provision in prison has improved but challenges remain: findings from a national survey in England eight years after the 2014 Care Act. [PDF]

BMC Public Health
Buck D, O'Neill A, Marsh N, Stalker K, Plugge E, Hargreaves C, Brimblecombe N, Harriott P, Robinson C, Shaw JJ, Forsyth K.   +10 more
europepmc   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Impact of the Strengthening Teamwork and Respect (STAR) intervention on organisational learning culture and person-centred maternity care in rural South Africa: an uncontrolled before-and-after implementation study.

Lancet Reg Health Afr
Doherty T, Filippi V, John V, Haskins L, Land S, Phewa C, Mapumulo S, Luthuli S, Penn-Kekana L, Manda S, Moran N, Sibiya R, Myeza H, Horwood C.   +13 more
europepmc   +1 more source

Pregnant women's acceptability of intermittent preventive treatment with dihydroartemisinin-piperaquine from user and provider's perspectives: qualitative findings from the pilot implementation in Papua, Indonesia. [PDF]

BMC Pregnancy Childbirth
Hoyt J, Candrawati F, Hafidz F, Mulyadi AWE, Kenangalem E, Laksanawati IS, Ubra R, Poespoprodjo JR, Hill J.   +8 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Health system readiness for immediate Kangaroo Mother Care (iKMC) among network of care facilities in the Sidama region, Ethiopia: a mixed-method study. [PDF]

Gates Open Res
Estifanos AS, Negash H, Getachew S, Keraga DW, Alemayehu A, Argaw MS, Solomon M, Belay FW, Rettedal S, Yoshida S, Portela A.   +10 more
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Perceptions of Nurse Managers and Supervisors on the Scope of Nursing Practice Following the 2023 National Regulatory Update in Saudi Arabia: A Qualitative Study in Makkah Cluster Hospitals. [PDF]

Healthcare (Basel)
Alfahmi HM, Kerari A.
europepmc   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

The structure of classes in Uruguay, 1963-1996: a structural-historical perspective. [PDF]

Front Sociol
Boado M, Vanoli S, Rey R.
europepmc   +1 more source