Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys +6 more
wiley +1 more source
Menopause and the healthcare workforce: a scoping review and stakeholder consultation. [PDF]
Scott J +4 more
europepmc +1 more source
Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni +4 more
wiley +1 more source
"I can't just talk it. I have to live it": the roles, needs, and recruitment of recovery home house managers. [PDF]
Zoschke IN +6 more
europepmc +1 more source
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Flexible Work and Organizational Commitment Among Korean Managers: The Mediating Role of Work-Family Conflict and CEO Gender Equality. [PDF]
Kim H, Lee JS.
europepmc +1 more source
ELABELA Targets Mitochondria to Modulate Heart Development
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
HOme-based self-sampling for cervical cancer prevention education among women living with HIV in Ghana (HOPE-inG): study protocol for a cluster-randomized type 2 hybrid effectiveness implementation trial. [PDF]
Asare M +12 more
europepmc +1 more source
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source

