Results 51 to 60 of about 74,447 (294)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Moisture conditions in coated wood panels during 24 months natural weathering at five sites in Europe [PDF]

open access: yes, 2013
Wood moisture content of coated panels of Scots pine sapwood was recorded during 24 months natural weathering in Vienna by logging electric resistance and temperature near the surface.
De Windt, Imke001997427636801001686847977933927060F69770B2-F0ED-11E1-A9DE-61C894A0A6B4   +6 more
core   +1 more source

Formaldehyde-Free Resins for the Wood-Based Panel Industry: Alternatives to Formaldehyde and Novel Hardeners

open access: yesMolecules, 2022
Due to its carcinogenic properties, the presence of formaldehyde in resins and other industrial products has been a subject of great concern in recent years. The presented review focuses on modern alternatives for the production of wood-based panels; i.e.
Justyna Chrobak   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Preparation and Characterization of Wood Composites for Wood Restoration [PDF]

open access: yes, 2023
Given the widespread use of wood-based materials and that these materials are often damaged, an abundance of materials have been developed to repair and restore wood.
Tianyuan Chen   +3 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Wood-based panels for land transport uses [PDF]

open access: yes, 2015
Wood-based panels are widely used in the transport sector, thanks in particular to their properties in terms of lightness and mechanical strength. Furthermore, they offer additional benefits, such as sound insulation or fire resistance. The present paper
Zanuttini, Roberto   +5 more
core   +1 more source

Evaluation of wheat straw for the development of bio-based panels

open access: yesDiscover Materials
This study explores the potential of wheat straw (Triticum aestivum) for producing structural panels suitable for use in the building industry. The research was motivated by the large volume of agricultural waste that is commonly underutilized or burned,
Arun Kuttoor Vasudevan   +5 more
doaj   +1 more source

Development of Veneer-based Corrugated Composites, Part 1: Manufacture and Basic Material Properties

open access: yesBioResources, 2016
Typically, wood-based composite materials have been developed through empirical studies. In these products, the constituent wood elements have broad spectrums regarding species, size, and anatomical orientation relative to their own dimensions. To define
Levente Denes   +2 more
doaj   +1 more source

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