Results 71 to 80 of about 19,225 (255)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Substrate in the emergence and initial growth of seedlings of Caesalpinia pulcherrima

Ciência Rural
: Caesalpinia pulcherrima is an exotic species belongs to the Fabaceae family commonly known as flamboyant-mirim, and widely used for urban forestry. This study aimed to evaluate the effect of different substrates on the emergence and early seedlings ...
Magnólia Martins Alves, Edna Ursulino Alves, Luciana Rodrigues de Araújo, Maria de Lourdes dos Santos Lima   +3 more
doaj   +1 more source

Explosivity Properties of Dusts from Torrefied Biomass Pellets

Chemical Engineering Transactions, 2016
A modified Hartmann tube apparatus was used to study the explosivity properties of dusts from torrefied biomass pellets. The sensitivity of the dusts to explode was assessed by determining the minimum ignition energies (MIE) and the minimum explosible ...
Pedro Abelha, Mariusz Cieplik, Michiel Carbo   +2 more
doaj   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Occupational exposure to wood dust and formaldehyde and risk of nasal, nasopharyngeal, and lung cancer among Finnish men

Cancer Management and Research, 2012
Sie Sie Siew,1,2 Timo Kauppinen,1 Pentti Kyyrönen,3 Pirjo Heikkilä,1 Eero Pukkala2,31Finnish Institute of Occupational Health, Helsinki, Finland; 2School of Health Sciences, University of Tampere, Tampere, Finland; 3Finnish Cancer ...
Siew SS, Kauppinen T, Kyyrönen P, Heikkila P, Pukkala E   +3 more
doaj  

PAPAN GYPSUM DARI SERBUK KAYU DAN SENYAWA BOR TERHADAP SIFAT MEKANIK DAN UJI BAKAR

Jurnal Riset Industri Hasil Hutan, 2012
The using saw dust Lua, Kambang, Tarap wood and addition of boron solution on Modulus of Rupture (MOR), Modulus of Elasticity (MOE) and the fire  resistant gypsum boar.
Djoko Purwanto
doaj   +1 more source

Upcycling of Wood Dust from Particleboard Recycling as a Filler in Lignocellulosic Layered Composite Technology. [PDF]

Materials (Basel), 2023
Wronka A, Kowaluk G.
europepmc   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

Advanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi, Kateryna Andriienkova, Tetyana Goldanova, Ezgi Antmen, Thibaut Soubrie, Nihal Engin Vrana   +5 more
wiley   +1 more source