Results 31 to 40 of about 1,201,104 (309)

A tough and robust hydrogel constructed through carbon dots induced crystallization domains integrated orientation regulation

open access: yesNature Communications
Tough hydrogels show great potential applied in flexible electronics, sensors and soft robotics, but it remains challenging to combine high strength, toughness and stability.
Huanxin Huo   +11 more
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Bonding performance and surface characterization of cold-bonded acetylated beech (Fagus sylvatica L.) laminated veneer lumber

open access: yesScientific Reports
Acetylation of wood with acetic anhydride reduces the wood–moisture interaction, improves the dimensional stability and resistance against biodegradation.
Maik Slabohm, Holger Militz
doaj   +1 more source

Moisture behaviour and biological durability of wood‐polymer composites [PDF]

open access: yes, 2009
In recent years wood-polymer composites appears at the European market more frequently, mainly in decking applications as an alternative for durable tropical hardwood decking.
Defoirdt, Nele   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Non-twist flax fibre reinforcement of lightweight plywood

open access: yesDiscover Applied Sciences
Using lignin-phenol-formaldehyde (LPF) impregnated flax fibres is a little-studied method for reinforcing plywood through natural materials with only a modest increase in density.
Marcus Cordier, Ole Gonnsen, Carsten Mai
doaj   +1 more source

Wood Products and Carbon Storage: Can Increased Production Help Solve the Climate Crisis? [PDF]

open access: yes, 2009
This report draws on a variety of sources to illuminate the greenhouse gas impacts of wood products and wood biomass fuels throughout their life-cycles.
Ann Ingerson
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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