Results 31 to 40 of about 1,106,534 (306)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Effects of torrefaction on energy properties of Eucalyptus grandis wood [PDF]

open access: yes, 2009
Torrefaction is a thermal treatment that promotes homogenization and improvement of energy properties of biomass. This study aims to evaluate the effects of torrefaction on the main energy properties of Eucalyptus grandis wood.
Oliveira Rodrigues, Thiago   +1 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Influence of anatomy and basic density on specific cutting force for wood from Corymbia citriodora Hill & Johnson

open access: yesForest Systems, 2015
Aim of the study: The aim of this study was to evaluate the influence of xylem tissue cell structure, determined through biometry and basic density of the wood from Corymbia citriodora Hill & Johnson on consumption of specific 90º-0º longitudinal ...
Luiz-E. de L. Melo   +4 more
doaj   +1 more source

Moisture content analysis of wooden bridges [PDF]

open access: yes, 2019
The article deals with assessing the impact of moisture content conditions in wood mass of the wood bridges constructions on their lifespan in Central Europe.
Fojtík, Roman
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Eco-friendly approach and potential biodegradable polymer matrix for WPC composite materials in outdoor application [PDF]

open access: yes, 2019
Blends based on high density polyethylene (HDPE) and poly(lactic) acid (PLA) with different ratios of both polymers were produced: a blend with equal amounts of HDPE and PLA, hence 50 wt.% each, proved to be a useful compromise, allowing a high amount of
Massardier, Valerie   +2 more
core   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Evaluation of the carbon sink potential of wooden foundation piles embedded in oxygen-depleted soils using density profile analysis

open access: yesJournal of Wood Science
Wooden foundation piles are a renewable resource that contributes to mitigating climate change because of the minimal processing requirements and remarkably long service life.
Ikuo Momohara   +4 more
doaj   +1 more source

Effects of potassium/sodium fertilization and water availability on wood properties of Eucalyptus grandis trees [PDF]

open access: yes, 2019
In Brazil. most Eucalyptus plantations are located in regions experiencing periods of water shortage where fertilizers such as potassium (K) are intensively used to achieve high productivity. Recently.
Chaix, Gilles   +2 more
core  

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