Results 51 to 60 of about 1,631,332 (313)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Utilization of temperature kinetics as a method to predict treatment intensity and corresponding treated wood quality : durability and mechanical properties of thermally modified wood [PDF]

, 2014
Wood heat treatment is an attractive alternative to improve decay resistance of wood species with low natural durability. However, this improvement of durability is realized at the expense of the mechanical resistance.
CANDELIER, Kévin, COLLET, Robert, DUMARÇAY, Stéphane, ELAIEB, Mohamed, GERARDIN, Phillipe, HANNOUZ, Simon, PETRISSANS, Anelie, PETRISSANS, Mathieu   +7 more
core   +7 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Variação axial e efeito do desbaste na massa específica das árvores centrais de Eucalyptus grandis Axial variation and effect of thinning on basic density of central trees of Eucalyptus grandis

Ciência Rural, 2012
Este estudo teve como objetivo avaliar a variação axial e o efeito do desbaste na massa específica das árvores centrais de Eucalyptus grandis aos 18 anos de idade.
Rômulo Trevisan, Elder Eloy, Luciano Denardi, Clovis Roberto Haselein, Braulio Otomar Caron   +4 more
doaj  

Reducing Black Carbon from Wood Burning in Fairbanks, Alaska [PDF]

, 2014
Fairbanks, Alaska has been home to air quality concerns for years. Heat sources like wood boilers emit black carbon, a pollutant akin to soot. In Fairbanks\u27s harsh winters, black carbon is trapped close to the earth and creates health problems for ...
Beaudoin, Kristine J.
core   +1 more source

Predicting microfibril angle in Eucalyptus wood from different wood faces and surface qualities using near infrared spectra [PDF]

, 2010
International audienceThe microfibril angle (MFA) of crystalline cellulose in the wood cell wall along the stem axis has major effects on stiffness and longitudinal shrinkage of wood and is of key importance to timber quality. The aims of this study were:
Brancheriau, Loïc, Chaix, Gilles, Clair, Bruno, Hein, Paulo Ricardo Gherardi   +3 more
core   +3 more sources

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Monitoring and modeling of household air quality related to use of different Cookfuels in Paraguay. [PDF]

, 2019
In Paraguay, 49% of the population depends on biomass (wood and charcoal) for cooking. Residential biomass burning is a major source of fine particulate matter (PM2.5 ) and carbon monoxide (CO) in and around the household environment. In July 2016, cross-
Balmes, John, Galeano, Aida, Hernandez, Maria Teresa, Oyola, Pedro, Pillarisetti, Ajay, Smith, Kirk R, Soares, Agnes, Tagle, Matias, Torres, Ricardo, Troncoso, Karin   +9 more
core   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Cadmium enrichment influences cell wall properties and leaching resistance of tension and opposite wood in poplar

Industrial Crops and Products
Poplar is a high-biomass species and is widely used for the phytoremediation of soils contaminated with cadmium. It is often subjected to heterogeneous soil conditions and associated stresses that promote reaction wood formation during growth.
Zekai Sun, Pengfei Xia, Manman Lu, Chunping Dai, Jiejie Sun, Jing Qian   +5 more
doaj   +1 more source