Results 41 to 50 of about 18,202 (245)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Anatomical, morphological and chemical properties of Tobacco stalk (Nicotiana tabacum L.) [PDF]

تحقیقات علوم چوب و کاغذ ایران, 2012
Tobacco (Nicotiana tabacum) is one of the non-wood species and its stalks are the main crop after harvesting  which can be used in composite board and paper industry.
Vahid Safdari, Seyyed Peyman Hashemi Beygzadmahalleh, Asghar Tabei, Seyyed Khalil Hosseinihashemi   +3 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Impact of tree age on values of selected parameters and structural indices of wood fibres of silver birch (Betula pendula Roth.) in Poland

Industrial Crops and Products
Silver birch is one of the most important forest-forming tree species in Poland and north-eastern Europe. Birch fibres are a major source of paper and fibre-based products.
Hubert Lachowicz, Monika Zielińska-Sitkiewicz, Patrycja Kulak   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Qualitative and Quantitative Anatomical Characteristics and Radial Variation of Major Cell Components in Paulownia tomentosa Wood Grown in Korea

BioResources
Qualitative and quantitative anatomical characteristics and radial variations of the major cell components in Paulownia tomentosa wood were examined using optical microscopy and X-ray diffraction to aid in wood identification and as quality indices.
Jae Ik Jo, Byantara Darsan Purusatama, Yue Qi, Nam Hun Kim   +3 more
doaj   +2 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Integrating Proximal Sensing Data for Assessing Wood Distillate Effects in Strawberry Growth and Fruit Development

Horticulturae
Strawberry (Fragaria × ananassa (Weston) Rozier) is a high-value crop whose market success depends on fruit quality traits such as sweetness, firmness, and pigmentation.
Valeria Palchetti, Sara Beltrami, Francesca Alderotti, Maddalena Grieco, Giovanni Marino, Giovanni Agati, Ermes Lo Piccolo, Mauro Centritto, Francesco Ferrini, Antonella Gori, Vincenzo Montesano, Cecilia Brunetti   +11 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source