Results 91 to 100 of about 4,315 (169)

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small‐Cell Lung Cancer Models

Cancer Science, EarlyView.
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi, Miyuki Nomura, Mai Ouchi, Shigehiro Yagishita, Naohiko Kikuchi, Taku Sato, Mami Morita, Yoji Yamashita, Kayoko Hayashi, Tomoyoshi Soga, Akinobu Hamada, Tatsuro Fukuhara, Nobuhiro Tanuma   +12 more
wiley   +1 more source

A revised classification system of the marronoid clade of spiders (Araneae), based on dense sampling phylogenomics and comparative morphology

Cladistics, EarlyView.
Abstract The marronoid clade is a globally distributed, ecologically diverse group of spiders. It is an important faunal component in both natural and synanthropic environments, and even found in aquatic and extreme habitats such as desert salt flats. The systematics of the marronoid clade has been notoriously unstable due to the widespread character ...
Jonas O. Wolff, Michael B. J. Kelly, Franklyn Cala‐Riquelme, Jacob A. Gorneau, Katherine O. Montana, Helen M. Smith, Phil J. Sirvid, Cor J. Vink, Lauren A. Esposito, Martín J. Ramírez, Charles E. Griswold   +10 more
wiley   +1 more source

Effects of restoration practices on biodiversity in temperate and boreal forests

Conservation Biology, EarlyView.
Abstract Several restoration practices are used to mitigate and compensate for the negative effects of large‐scale forestry on biodiversity in temperate and boreal forests. A comprehensive synthesis of the benefits of these practices across taxa is missing. We conducted a systematic review and meta‐analysis on this topic.
Malin Tälle, Thomas Ranius, Julia Koricheva   +2 more
wiley   +1 more source

Biotic and Abiotic Factors Controlling Respiration Rates of Above- and Belowground Woody Debris of Fagus crenata and Quercus crispula in Japan. [PDF]

PLoS One, 2015
Jomura M, Akashi Y, Itoh H, Yuki R, Sakai Y, Maruyama Y.   +5 more
europepmc   +1 more source

Using a Generic Blend of Pheromones to Simultaneously Attract a Diversity of Elaterid Beetle Species Native to Eastern North America

Entomologia Experimentalis et Applicata, EarlyView.
We assessed attraction of eight elaterid species to a “generic” pheromone blend containing their eight known pheromones or sex attractants. All eight species were attracted by their specific attractants, as expected. Six species were attracted to the blend, but the remaining two species were strongly inhibited by unknown blend components.
Rachel M. Rusen, Jocelyn G. Millar, Thomas C. McElrath, Lawrence M. Hanks   +3 more
wiley   +1 more source

Coarse Woody Debris Increases Microbial Community Functional Diversity but not Enzyme Activities in Reclaimed Oil Sands Soils. [PDF]

PLoS One, 2015
Kwak JH, Chang SX, Naeth MA, Schaaf W.
europepmc   +1 more source

Landscape and Geography Determine Saproxylic Beetle Captures in Pheromone‐Baited Traps

Entomologia Experimentalis et Applicata, EarlyView.
Pheromone‐baited traps at 39 forest sites across southern Sweden captured 58 saproxylic beetle species, including seven Red‐listed taxa. The effect of surrounding forest cover on beetle abundance may depend on latitude and longitude: positive effects were strongest in warmer southern and eastern regions but weakened or reversed in colder northwestern ...
Markus Franzén, Christoffer Fristedt, Olof Persson, Per Milberg, Victor Johansson   +4 more
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Tree identity shapes composition, substrate shifts dominance in deadwood fungi of an old-growth lowland beech forest. [PDF]

IMA Fungus
Dierickx G, Vandekerkhove K, Van de Kerckhove P, Asselman P, Verbeken A.   +4 more
europepmc   +1 more source

Structural and thermodynamic analyses of a novel β‐1,2‐glucan binding mode in the ABC transporter solute‐binding protein Chy400_4166 from Chloroflexus aurantiacus

The FEBS Journal, EarlyView.
Cyclic β‐1,2‐glucan (CβG)‐associated solute‐binding protein of type I ABC transporter was originally identified in Chloroflexus aurantiacus, a phototrophic bacterium. Crystal structures in complex with CβGs revealed unique binding modes that are fundamentally distinct from that of the short β‐1,2‐glucooligosaccharides‐binding protein.
Kazuya Kato, Tatsuya Kaneko, Rintaro Hirayama, Nobukiyo Tanaka, Hiroyuki Nakai, Hidetaka Torigoe, Masahiro Nakajima   +6 more
wiley   +1 more source