Results 51 to 60 of about 987,359 (249)

Head-Mounted Display-Based Microscopic Imaging System with Customizable Field Size and Viewpoint

open access: yesSensors, 2020
In recent years, the use of microinjections has increased in life science and biotechnology fields; specific examples include artificial insemination and gene manipulation.
Tadayoshi Aoyama   +3 more
doaj   +1 more source

Palaearctic origin of Leishmania [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 2000
The hypothesis of a Palaearctic origin of Leishmania in the early Cenozoic, dispersal to the Nearctic in the late Eocene and to the Neotropical in the Pliocene is presented. It is further hypothesized that murid rodents and their immediate ancestors have
Sara F Kerr
doaj   +1 more source

Perception of Eco-innovation Based on Educational Attainment

open access: yesEuropean Management Studies, 2023
Aim: To evaluate the influence of educational attainment on the perception of ecological innovation was the main objective of the paper. The depth of attention paid to the interdisciplinary impact of innovations and education in society ultimately ...
Erika Loučanová   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Students’ Use and Perceptions of a Due Date Extension Policy

open access: yesJournal of Effective Teaching in Higher Education, 2023
Students may sometimes benefit from due date extensions due to significant extenuating circumstances. These circumstances, though, may not be supported by documentation as required by university policies.
Stefanie Boswell
doaj   +1 more source

Word Activation Forces Map Word Networks [PDF]

open access: yes, 2011
Words associate with each other in a manner of intricate clusters^1-3^. Yet the brain capably encodes the complex relations into workable networks^4-7^ such that the onset of a word in the brain automatically and selectively activates its associates ...
Jun Guo, Hanliang Guo, Zhanyi Wang
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

COVID-19-associated familial acute disseminated encephalomyelitis (ADEM): A case report

open access: yesIDCases, 2021
Background: Several neurological complications are being reported in hospitalized patients with severe COVID-19 infection. This is presumed due to direct spread of infection or due to immunological response. Acute disseminated encephalomyelitis (ADEM) is
Sivaram Neppala   +4 more
doaj   +1 more source

Inclusive Inquiry. 14th Annual Research Week: Event Proceedings [PDF]

open access: yes, 2021
Presentations of completed and ongoing research activity conducted by graduate and undergraduate students and faculty at University of the Incarnate Word.
University of the Incarnate Word
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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