Results 221 to 230 of about 17,489,457 (273)

DTX3 Suppresses the NPM3–RUVBL1 Axis to Inhibit Homologous Recombination Repair and Abrogate Tumor Radioresistance

open access: yesAdvanced Science, EarlyView.
Deltex 3 (DTX3) catalyzes K27‐linked ubiquitination of nucleophosmin 3 to disrupt homologous recombination repair and reverse tumor radioresistance. Low DTX3 predicts poor survival and radiotherapy recurrence, serving as a radiosensitizing therapeutic target.
Jia‐Hao Xiao   +9 more
wiley   +1 more source

Electrocatalytic Urea Synthesis From CO2 and N2/NO3−: Bridging Catalyst Activity, C–N Coupling Kinetics, and Industrial Applicability

open access: yesAdvanced Science, EarlyView.
This review compares NO3− + CO2 and N2 + CO2 electrocatalytic urea synthesis in feedstock properties, catalyst design, C–N coupling mechanisms, performance optimization, and engineering applicability. The two systems correspond to a near‐term deployable route and a long‐term green synthesis goal, respectively.
Fulin Dong   +5 more
wiley   +1 more source

Rethinking Cochlear Implants: The Need for Precise Temporal Coding

open access: yesAdvanced Science, EarlyView.
Spatial hearing relies on sensitivity to interaural temporal cues, but this sensitivity is often poorly developed in patients with cochlear implants, particularly those with early‐onset hearing loss. Rats with cochlear implants, however, demonstrate excellent temporal sensitivity, suggesting that this limitation is not inevitable.
Nicole Rosskothen‐Kuhl   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy