Results 41 to 50 of about 25,624 (260)

Analysing the Methods of Dzongkha Word Segmentation

open access: yesApplied Computer Systems, 2017
In both Chinese and Dzongkha languages, the greatest challenge is to identify the word boundaries because there are no word delimiters as it is in English and other Western languages.
Dhungyel Parshu Ram   +1 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Contextual dependencies in unsupervised word segmentation [PDF]

open access: yesProceedings of the 21st International Conference on Computational Linguistics and the 44th annual meeting of the ACL - ACL '06, 2006
Developing better methods for segmenting continuous text into words is important for improving the processing of Asian languages, and may shed light on how humans learn to segment speech. We propose two new Bayesian word segmentation methods that assume unigram and bigram models of word dependencies respectively.
Sharon Goldwater   +2 more
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Synthetic Word Parsing Improves Chinese Word Segmentation [PDF]

open access: yesProceedings of the 53rd Annual Meeting of the Association for Computational Linguistics and the 7th International Joint Conference on Natural Language Processing (Volume 2: Short Papers), 2015
We present a novel solution to improve the performance of Chinese word segmentation (CWS) using a synthetic word parser. The parser analyses the internal structure of words, and attempts to convert out-of-vocabulary words (OOVs) into in-vocabulary fine-grained sub-words.
Fei Cheng 0002   +2 more
openaire   +2 more sources

Enhancing Sindhi Word Segmentation Using Subword Representation Learning and Position-Aware Self-Attention

open access: yesIEEE Access
Sindhi word segmentation is a challenging task due to space omission and insertion issues. The Sindhi language itself adds to this complexity. It’s cursive and consists of characters with inherent joining and non-joining properties, independent of
Wazir Ali   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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