Results 121 to 130 of about 1,338,925 (305)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The mediating effect of work-life balance on the relationship between work-family conflict and psychological well-being among Chinese working women

Scientific Reports
The study aims to explore whether work-life balance mediates the impact of work-family conflict and its dimensions on psychological well-being. Using a survey method, data were collected from a sample of 258 working women in Hebei province in China.
Xiaoying Bian, Mohammad Saipol Mohd Sukor   +1 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The Relationship between Quality of Working Life and Work-family Conflict among Nurses of Tehran University of Medical Sciences\' Hospitals

بیمارستان, 2015
Background: Nowadays, quality of working life as a universal concept of human resource management and organizational development have been regarded and improving it, is key to successfully managing any organization.
Amir Ashkan Nasiripour, Mehrak Pourmotahari   +1 more
doaj  

A Shifting Paradigm of Work-Life Balance in Service Context-An Empirical Study [PDF]

Purpose: The study examined the effect of various ‘work-life balance’ determinants such as employee benefits, work environment, workload, flextime and discrimination on work culture and job satisfaction.
A.K.M.Mominul Haque Talukder
core  

Work-Family Conflict Chinese Style

, 2023
This thesis aimed to examine work-family conflict within China by conducting two studies. This thesis utilised 536 participants, 16 of whom participated in the semi-structured online interviews of Study 1 which explored the lived experience of work ...
Chen, Shujie
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Family cyberloafing and work-life balance: digital coping with work–family conflict across generations

Business: Theory and Practice
Work-family conflict (WFC) often undermines employees’ well-being, yet the coping role of family-related cyberloafing (FCL) across generations remains unclear.
Ahyar Yuniawan, Fuad Mas'ud, Muhamad Syaichu, Rosaly Franksiska   +3 more
doaj   +1 more source

The role of psychosocial safety climate on flexible work from home digital job demands and work-life conflict. [PDF]

Ind Health, 2023
Parkin AK, Zadow AJ, Potter RE, Afsharian A, Dollard MF, Pignata S, Bakker AB, Lushington K.   +7 more
europepmc   +1 more source

The effect of work-life balance policies on women employees turnover [PDF]

In this paper, we explore the relationship between work-life balance policies and three outcomes of interest to employers and employees: the job tenure of women employees, turnover rate of women employees and retention rate of new women graduates. In the
Noriaki Mamiko Takeuchi, Chiang Hui-Yu
core