Results 161 to 170 of about 1,546,440 (328)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

702 A tailored work- related support intervention for gastro-intestinal cancer patients: intervention protocol [PDF]

, 2018
AnneClaire G. N. M. Zaman, Angela G. E. M. de Boer, Kristien M.A.J. Tytgat, Jean H. G. Klinkenbijl, Monique H. W. Frings‐Dresen   +4 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Global, regional and national burdens of non-melanoma skin cancer attributable to occupational exposure to solar ultraviolet radiation for 183 countries, 2000–2019: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury

, 2023
Frank Pega, Natalie C. Momen, Kai Nino Streicher, Maria Léon-Roux, Subas Neupane, Mary K. Schubauer‐Berigan, Joachim Schüz, Marissa G. Baker, Tim Driscoll, Irina Guseva Canu, Hannah M. Kiiver, Jian Li, Jamaji C. Nwanaji‐Enwerem, Michelle C. Turner, Susana Viegas, Paul J. Villeneuve   +15 more
openalex   +2 more sources

Tailored work-related support for patients with gastrointestinal cancer

, 2019
Almost half of the patients with cancer are of working age and their survival rate is steadily increasing. Due to the increasing retirement age, the number of cancer survivors in the working population will rise. Although (return-to) work-related problems are experienced even at diagnosis, there are no support interventions yet at that particular ...
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Diagnostic and Prognostic Value of Myocardial Work Indices for Identification of Cancer Therapy-Related Cardiotoxicity.

JACC Cardiovascular Imaging, 2022
O. Calvillo-Argüelles, B. Thampinathan, E. Somerset, Tamar Shalmon, E. Amir, Chun-Po Steve Fan, Sangkyu Moon, H. Abdel-Qadir, Y. Thevakumaran, J. Day, A. Woo, B. Wintersperger, T. Marwick, P. Thavendiranathan   +13 more
semanticscholar   +1 more source

Understanding Return to Work After a Cancer‐Related Sickness Absence. Perceptions of Barriers and Facilitators Among all Relevant Stakeholders [PDF]

Amaya Ayala‐García, Laura Serra, Dolors Rodríguez-Arjona, Fernando G. Benavides, Mireia Utzet   +4 more
openalex   +1 more source

Health-related quality of life and work productivity in UK patients with HER2-positive breast cancer: a cross-sectional study evaluating the relationships between disease and treatment stage [PDF]

, 2020
Mark Verrill, Andrew Wardley, Jenny Retzler, Adam B. Smith, Catherine Bottomley, Sorcha Ní Dhochartaigh, Irwin Tran, I Leslie, Peter Schmid   +8 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source