Results 121 to 130 of about 40,520,256 (406)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Trajectories of Wok Adjustment and Influencing Factors Among Newly Registered Nurses

open access: yesAsian Nursing Research
Summary: Purpose: This study explored the work adjustment trajectory and its predictors and characteristics among newly registered nurses. Methods: A total of 245 newly registered nurses working in a university hospital provided general baseline ...
Sunghee Park   +5 more
doaj   +1 more source

Whistleblowing: the inside story - a study of the experiences of 1,000 whistleblowers [PDF]

open access: yes, 2013
This report presents the findings of a collaborative research project by the University of Greenwich and Public Concern at Work, on how the whistleblowing process develops from internal to external whistleblowing.
James, Cathy   +4 more
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

PREVENTIVE DETENTION AT WORK.* [PDF]

open access: bronze, 1921
F. E. WINTLE
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Work-Family Conflict and Job Satisfaction: the Mediating Role of Person-Organization Fit Study on Employees of the BRI Aceh Region [PDF]

open access: yes, 2016
The objective of this research is to analyze the influence of person–organizationfit (P-O fit) on work–family conflict (WFC) and job satisfaction (JS) relationships atBank Rakyat Indonesia, Aceh Regional in Banda Aceh.
Ibrahim, M. (Mahdani), Yusra, Y. (Yusra)
core  

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