Results 121 to 130 of about 8,220,892 (269)

Barriers and Facilitators to Participation in Interventions for Employee Health and Wellbeing in the University Context. [PDF]

Stress Health
Bailey A, Kooij D, de Reuver R, Kupper N.   +3 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Burnout and work-life balance: the generational points of view. [PDF]

Insights Imaging
Molwitz I, Korchi AM, Gheonea IA, Curvo-Semedo L, D'Anna G.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A scoping review and research agenda: Psychological flexibility and wellbeing in organisations. [PDF]

Appl Psychol Health Well Being
Roche M, Faulkner JW, Callagher E.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Roads to recognition: experiences of migrant women healthcare workers in Norwegian nursing homes. [PDF]

Scand J Prim Health Care
Hedlund Quintanilla CT, Jerve Ramsøy I, Fadnes Jacobsen F, Van den Bergh G.   +3 more
europepmc   +1 more source

A Critique of Capitalism? The Mediation of Abstract Labour in Yvonne Rainer’s Task-Dance

Parse Journal, 2019
Josefine Wikström
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tailored job coaching for people with severe mental illness living in supported housing settings: A realist approach. [PDF]

PLoS One
Binkhorst J, Dikkers J, Blonk R, van Veldhoven M.   +3 more
europepmc   +1 more source