Results 101 to 110 of about 17,090,963 (294)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

2011 Agenda: The 23rd National Symposium on Doctoral Research in Social Work

open access: yes, 2011
The Ohio State University College of Social ...
Ohio State University. College of Social Work
core  

Ecosocial Work and Sustainability Transitions

open access: yes
Sustainable development and ecosocial work have become one of the most dynamic global debates of the social work profession. How can social work contribute to the sustainability transitions of European societies?

core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

2007 Photo Gallery: The 19th National Symposium on Doctoral Research in Social Work

open access: yes, 2007
The University Archives has determined that this item is of continuing value to OSU's history.The Ohio State University College of Social ...
Ohio State University. College of Social Work
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Maurine E. Work

open access: yes, 2007
"SF 6475[6] L/Cpl Maurine E. Work. AWAS = H.Q. Signals Unit. 1943-1945. Alice Springs. [Signature] Maurine Work".SF 6475[6] Lance Corporal Maurine E. Work. Australian Women's Army Service Headquarters Signals Unit. 1943-1945. Alice Springs.
Work, Maurine E
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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