Results 101 to 110 of about 22,546,048 (294)

The practical application of sexual literacy to social work

open access: yes, 2017
The social work literature has experienced a dramatic and increasingly widespread interest in human sexuality. “Basic understanding of human sexuality…is a necessary part of the professional education of the social worker,” (Abramowitz, 1971, p. 353-354).
Thompson, Michelle G.   +3 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Empathy in social work

open access: yes, 2017
A dominant conceptualization of empathy in social work practice and education, provided by Karen Gerdes and Elizabeth Segal, relies heavily on the simulation theory adopted directly from the cognitive neurosciences.
Eriksson, Karl,   +6 more
core   +1 more source

The Implementation of Social Work Practice with Children in Indonesia [PDF]

open access: yes, 2017
This study aimed at examining the implementation of social work practice with children in Indonesia. The research used qualitative method with a case study on nine informants who were Social Workers carrying out the task of handling children cases in the
Subardhini, Meiti   +5 more
core   +1 more source

Unpacking AI at work: Data work, knowledge work, and values work

open access: yesInformation and Organization
The rise of data-driven artificial intelligence (AI) technologies has sparked intense debates about their implications for work. These discussions often portray AI as an agentic force that turns data into knowledge and ultimately, “better” decisions, casting shadows over the labor that sustains and supports these technologies. This paper argues that to
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

United War Work Campaign Opening Rally pamphlet, November 8, 1918

open access: yes, 1918
This 20-page pamphlet is for the Opening Rally of the United War Work Campaign held on November 8, 1918. The rally was held at the Medinah Temple in Chicago. The pamphlet has the order of events, posters used by all seven of the organizations involved in
United War Work Campaign;
core  

Knowledge work as occupational strategy: comparing IT and management consulting

open access: yes, 2006
Information technology and management consulting are two classic areas of knowledge work. Analysing them not in terms of 'essential traits' but occupational strategies addresses the problem of virtually all expert labour in the so-called information ...
Fincham, Robin
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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