Results 81 to 90 of about 32,017,528 (316)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Loops, matchings and alternating-sign matrices [PDF]
The appearance of numbers enumerating alternating sign matrices in stationary states of certain stochastic processes is reviewed. New conjectures concerning nest distribution functions are presented as well as a bijection between certain classes of ...
de Gier, Jan
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Art competitions as a tool for the promotion of INFODORADCA+ project [PDF]
The close relationship between visual arts and work issues has a long tradition in the world. At the beginning of the 20th century, first mass-produced photos were used in the fight for rights of people working in American factories. Nowadays, visual art
Agnieszka Szczygielska
doaj
Unpacking AI at work: Data work, knowledge work, and values work
The rise of data-driven artificial intelligence (AI) technologies has sparked intense debates about their implications for work. These discussions often portray AI as an agentic force that turns data into knowledge and ultimately, “better” decisions, casting shadows over the labor that sustains and supports these technologies. This paper argues that to
openaire +1 more source
Utilization of satellite data for inventorying prairie ponds and lakes. LANDSAT-1 data were used to discriminate ponds and lakes for waterfowl management [PDF]
The author has identified the following significant results. The mapping of open water as an indicator of waterfowl habitat quality was carried out by using two different recognition techniques, a single waveband thresholding approach and a multiple ...
Gilmer, D. S., Work, E. A., Jr.
core +1 more source

