Results 81 to 90 of about 32,017,528 (316)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Does ‘grief work’ work? [PDF]

open access: yesBereavement Care, 2003
Stroebe, W.   +2 more
openaire   +2 more sources

Loops, matchings and alternating-sign matrices [PDF]

open access: yes, 2003
The appearance of numbers enumerating alternating sign matrices in stationary states of certain stochastic processes is reviewed. New conjectures concerning nest distribution functions are presented as well as a bijection between certain classes of ...
de Gier, Jan
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Art competitions as a tool for the promotion of INFODORADCA+ project [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
The close relationship between visual arts and work issues has a long tradition in the world. At the beginning of the 20th century, first mass-produced photos were used in the fight for rights of people working in American factories. Nowadays, visual art
Agnieszka Szczygielska
doaj  

Unpacking AI at work: Data work, knowledge work, and values work

open access: yesInformation and Organization
The rise of data-driven artificial intelligence (AI) technologies has sparked intense debates about their implications for work. These discussions often portray AI as an agentic force that turns data into knowledge and ultimately, “better” decisions, casting shadows over the labor that sustains and supports these technologies. This paper argues that to
openaire   +1 more source

Utilization of satellite data for inventorying prairie ponds and lakes. LANDSAT-1 data were used to discriminate ponds and lakes for waterfowl management [PDF]

open access: yes
The author has identified the following significant results. The mapping of open water as an indicator of waterfowl habitat quality was carried out by using two different recognition techniques, a single waveband thresholding approach and a multiple ...
Gilmer, D. S., Work, E. A., Jr.
core   +1 more source

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