Results 91 to 100 of about 9,913,320 (301)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Graphdiyne as a Promising Substrate for Stabilizing Pt Nanoparticle Catalyst
At present, Pt nanoparticle catalysts in fuel cells suffer from aggregation and loss of chemical activity. In this work, graphdiyne, which has natural porous structure, was proposed as substrate with high adsorption ability to stabilize Pt nanoparticles.
Lin, Zheng-Zhe
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Shift work is a social phenomenon with adverse effects on the lives and health of people in various aspects. This adverse effect decreases shift workers’ ability over a time period.
Leila Ibrahimi Ghavamabadi +2 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The role of work ability and health on sustaining employability [PDF]
This thesis aimed to contribute to the understanding of the role of decreased work ability and ill health on work participation and work performance of older workers.
Berg, T.I.J. (Tilja) van den
core
Work ability of military police officers
OBJECTIVE: To determine the prevalence of work ability (WA) and describe characteristics of the subgroup with poor WA among military police officers. METHODS: A descriptive and cross-sectional study with 329 male military police officers engaged in street patrolling in Salvador, Bahia, Brazil, selected by proportionate stratified sampling.
Carla Requião Barreto +2 more
openaire +6 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Welfare Reform and Children's Short-Run Attainments: A Structural Approach [PDF]
In this paper, we develop a dynamic structural model of single mothers' work and welfare participation decisions while their children are young. This model is used to measure the effects of mothers' decisions on short run attainments of the children of ...
Chyi, Hau, Ozturk, Orgul
core +1 more source
Reflections on an intervention to motivate student learning through in-semester online assessment [PDF]
In my experience engineering degree programmes are relatively demanding in terms of class contact hours which are typically up to a factor of two greater than many equivalent arts based courses.
Laws, EM
core

