Results 101 to 110 of about 9,961,088 (302)

From Work Ability Research to Implementation [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2019
Work ability research started in Finland in the 1990s due to the challenges of work force aging. The employment rates of older workers (55+) were below 40% and early retirement and work disability rates were rather common in many European countries. The work ability concept and methods were developed and broad international research activities started ...
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Evaluating Variable Length Markov Chain Models for Analysis of User Web Navigation Sessions

open access: yes, 2006
Markov models have been widely used to represent and analyse user web navigation data. In previous work we have proposed a method to dynamically extend the order of a Markov chain model and a complimentary method for assessing the predictive power of ...
Borges, Jose, Levene, Mark
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Executive dysfunction in cerebral small vessel disease: A subdomain analysis with conventional and experimental assessment methods

open access: yesCerebral Circulation - Cognition and Behavior
Introduction: Executive functions and processing speed have been regarded as core cognitive domains affected in cerebral small vessel disease (SVD). Executive functions, as an umbrella concept, consist of a variety of different subcomponents, yet in ...
Hanna Jokinen   +10 more
doaj   +1 more source

Correlates of employment status in individuals with asthma: a cross-sectional survey

open access: yesJournal of Occupational Medicine and Toxicology, 2017
Background This study aims to elucidate factors that among adults with asthma are associated with working full-time. Methods This cross-sectional survey of 2613 working-age adults with asthma included questions on asthma history, symptoms and use of ...
Saara Taponen   +4 more
doaj   +1 more source

Welfare Reform and Children's Short-Run Attainments: A Structural Approach [PDF]

open access: yes
In this paper, we develop a dynamic structural model of single mothers' work and welfare participation decisions while their children are young. This model is used to measure the effects of mothers' decisions on short run attainments of the children of ...
Chyi, Hau, Ozturk, Orgul
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Heart Rate Variability in Sciatica Patients Referred to Spine Surgery

open access: yesGlobal Spine Journal, 2012
Introduction There is some data that pain patients may have impaired autonomic nervous system function assessed by heart rate variability (HRV). However, only few studies have evaluated the effect of low back disorders on HRV. In this study, we evaluated
J. Södervall   +6 more
doaj   +1 more source

Employee Satisfaction With Working Space and Its Association With Well-Being—A Cross-Sectional Study in a Multi-Space Office

open access: yesFrontiers in Public Health, 2019
Introduction: Different kinds of shared and activity-based offices are common today and employees' experiences, perceived health, well-being, satisfaction, and productivity have been studied in different types and sizes of environments.Objectives: In ...
Sirpa Lusa   +5 more
doaj   +1 more source

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