Results 71 to 80 of about 20,779,634 (277)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Workplace trauma exposure, emotional imbalance and work ability

open access: yes, 2009
Introduction: Exposure to workplace robbery is a very common and traumatic event among workers dealing with the public. Data is scarce about the association between exposure to robbery, robbery-related Post-traumatic Stress Disorder (PTSD) and work ...
G.P. Fichera   +3 more
core   +1 more source

Work Ability Index (WAI) of older workers: a review of selected Polish research [PDF]

open access: yes, 2017
W artykule przedstawiono analizę polskich badań prowadzonych w zakresie zdolności do pracy pracowników starszych ocenianych według WAI (Work Ability Index). Omówiono definicję starszego pracownika, a także zwrócono uwagę na związek pomiędzy zdolnością do
Malińska, M.
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Analytical evaluation of work ability index and its determining factors among workers of a car manufacturing industry

open access: yesSalāmat-i kār-i Īrān, 2012
Background and aims : The ability of work is the basis of well-being for all of us. Many factors affect the work ability such as work and work condition, work organization and human resource. The aim of this study was to assess the work ability among car
M Eyvazlou   +3 more
doaj  

Impact of work place stresses on work ability index in patients with depressive disorders

open access: yesMedicinski pregled, 2011
Introduction. Depression seriously affects one?s ability to perform work tasks and function at work. We studied the impact of both the individual and work factors on work ability index in patients suffering from depression. Material and methods.
Sanja Brekalo, Lazarević   +3 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Factors Associated To The Work Ability Among Brazilian Teachers

open access: yes, 2015
The aim of this research was to evaluate the work ability of school teachers and its relation to health, individual characteristics and working conditions. A cross-sectional study with a sample of 258 teachers (fundamental education and high school) from
Monteiro I., Vedovato T.G.
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Work ability index in a cohort of railway construction workers

open access: yes, 2005
Working conditions and work load can have a significant effect on work ability, due not only to their direct impact on health and well-being, but also to the possibility they let to maintain job and competence at acceptable levels with normal ageing.
G. Carpentiero   +3 more
core   +1 more source

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