Results 81 to 90 of about 993,040 (277)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Shift work, quality of life and work ability among Croatian hospital nurses [Smjenski rad, kvaliteta života i radna sposobnost kod medicinskih sestara u Hrvatskim bolnicama]

open access: yes, 2013
This paper is a report of a study of the associations of shift work with work ability and quality of life (QoL) among clinical nurses. A cross-sectional study was conducted in 2007-2008 on 1124 nurses using the Work Ability Index Questionnaire and the ...
Juras, Karin   +4 more
core  

Association between work ability and fatigue in Brazilian nursing workers

open access: yes, 2016
BACKGROUND: Impaired work ability is associated with work-related illnesses, early retirement and rising pension costs.\ud OBJECTIVE: To investigate the association between work ability and fatigue in nursing workers.\ud METHODS: Cross-sectional study ...
Silva, Fabio José da   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Factors Associated To The Work Ability Among Brazilian Teachers

open access: yes, 2015
The aim of this research was to evaluate the work ability of school teachers and its relation to health, individual characteristics and working conditions. A cross-sectional study with a sample of 258 teachers (fundamental education and high school) from
Monteiro I., Vedovato T.G.
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Disabled People At Work And Work Ability: A Study In A Brazilian Company

open access: yes, 2015
The inclusion of disabled people in society is a current concern in many countries. The objectiveofthis study wastoevaluate the work abilityofdisabled workers in comparison to non-disabled workers. The sample for this cross-sectional study consisted of a
Monteiro I., Hodge E.P.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Analytical evaluation of work ability index and its determining factors among workers of a car manufacturing industry

open access: yesSalāmat-i kār-i Īrān, 2012
Background and aims : The ability of work is the basis of well-being for all of us. Many factors affect the work ability such as work and work condition, work organization and human resource. The aim of this study was to assess the work ability among car
M Eyvazlou   +3 more
doaj  

Effort-Reward Imbalance and Work Ability Index among Italian female nurses : the role of family status

open access: yes, 2011
While research is mainly focused on the role of gender and biological/chronological age in the relationship between Work Ability Index and Effort/Reward Imbalance, this study addresses the association between work-related stress and work ability, taking
P. Campanini   +6 more
core  

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