Results 81 to 90 of about 938,233 (243)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Psychometric Properties of the Work Ability Index in Health Centre Workers in Spain. [PDF]
Mateo Rodríguez I +4 more
europepmc +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Work Ability Index of Forestry Machine Operators and some Ergonomic Aspects of their Work
This paper provides the results of an applied research of forestry machine operators related to their work ability index (WAI) and some ergonomic aspects of their everyday work. A questionnaire on work environment and working ability was conducted in the
Ivan Martinić +3 more
doaj
Obiettivo L’abilità lavorativa percepita rappresenta l’indice dell’interazione tra le risorse proprie del lavoratore e le richieste del profilo lavorativo che ricopre.
Carmelo Lorenzo Sgroi
doaj
Analysis of the Return to Work Program for Disabled Workers during the Pandemic COVID-19 Using the Quality of Life and Work Ability Index: Cross-Sectional Study. [PDF]
Kurnianto AA +5 more
europepmc +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Individual Work Attitudes and Work Ability
Work capacity depends on many factors, including the age and health status of the employee, but also on personal characteristics and attitudes, such as reduced tolerance of unfavorable working conditions (Work Annoyance, WA), excessive commitment to work
Nicola Magnavita +3 more
doaj +1 more source
Evaluation of work ability index and its association with job stress and musculoskeletal disorders among midwives during the Covid-19 pandemic. [PDF]
Amirmahani M +3 more
europepmc +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source

