Results 141 to 150 of about 13,693,389 (293)
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Addiction and Self-Determination: A Phenomenological Approach
In this article, I focus on possibly impaired self-determination in addiction. After some methodological reflections, I introduce a phenomenological description of the experience of being self-determined.
Schlimme, Jann E.
core +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
İŞKOLİKLİK ÜZERİNE BİR ARAŞTIRMA
Popüler basında işkoliklik kavramına önemli ilgi gösterilmesine rağmen, işkolikliğin anlaşılması için çok az sayıda araştırma yapılmıştır. Bu çalışmada, ilk olarak işkoliklik ve işkoliklik ile ilgili araştırmalar incelenmektedir.
Ferit Ölçer
doaj +2 more sources
Building a comprehensive understanding of 2SLGBTQ+ youth homelessness: a scoping review
Two-spirit, lesbian, gay, bisexual, transgender, queer, questioning, plus additional sexual and gender diverse (2SLGBTQ+) youth are overrepresented among youth experiencing homelessness.
Alex Abramovich +5 more
doaj +1 more source
Personality traits and the degree of work addiction among Polish women: the mediating role of depressiveness. [PDF]
Rachubińska K +6 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Perceptions of treatment needs : A factorial survey of Swedish addiction care practitioners
The aim of the study was to analyze addiction care staff (N=447) perceptions of needs for psychosocial and medical treatment, and possibilities for self-change in relation to fictitious cases. By means of a factorial survey and multilevel analysis, the
Samuelsson, Eva, Wallander, Lisa
core

