Results 121 to 130 of about 179,139 (288)

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Suicide among youth and young adults in Canada: bereaved parents’ perspectives on the systems of care

International Journal of Mental Health Systems
Background Suicide is the second leading cause of death among youth and young adults aged 15–24 in Canada. Emergency departments often serve as the first point of contact for identifying suicide risk, particularly for youth and young adults, partly due ...
Toula Kourgiantakis, Deborah Cooper, David Cooper, Shelley Craig, Eunjung Lee, Jori Jones, Carrie K. Y. Lau, Romy-Naïma Tousignant, Jonathan B. Singer, Marjorie Johnstone, Juveria Zaheer   +10 more
doaj   +1 more source

Hooked on the Internet: the prevalence, risk, theory and presenting problem of Internet addiction

, 2013
As the Internet becomes increasingly ubiquitous and mobile, Internet addiction appears as a potential mental health problem in adolescents and students.
Kuss, DJ
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Neurobiology of addiction /

, 2006
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years.
Koob, George F., Le Moal, Michel.
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Building a comprehensive understanding of 2SLGBTQ+ youth homelessness: a scoping review

International Journal for Equity in Health
Two-spirit, lesbian, gay, bisexual, transgender, queer, questioning, plus additional sexual and gender diverse (2SLGBTQ+) youth are overrepresented among youth experiencing homelessness.
Alex Abramovich, Nicole Elkington, Michael Silberberg, Nelson Pang, Rowen Stark, Sarah Bonato   +5 more
doaj   +1 more source

Vaccines against Vice: A constructive technology assessment of immunotherapies for addiction [PDF]

, 2011
This thesis examines the development of active immunotherapies or ‘vaccines’ for drug addiction, within the framework of constructive technology assessment.
Hobbs, Abbi
core