Results 51 to 60 of about 505,624 (288)

Medical Rhetoric and the Sympathetic “Inebriet”: 1870–1930 [PDF]

open access: yes, 2019
The modern view of addiction as a progressive brain disease originated in the second half of the 19th and early decades of the 20th centuries. Historians attribute the shift from a moral to a medical concept to the efforts of a small but well-organized ...
Reeves, Carol
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Managing high-risk behaviours and challenges to prevent housing loss in permanent supportive housing: a rapid review

open access: yesHarm Reduction Journal, 2023
Permanent supportive housing is an effective intervention for stably housing most people experiencing homelessness and mental illness who have complex support needs.
Nick Kerman   +8 more
doaj   +1 more source

A Systematic Review of Online Sex Addiction and Clinical Treatments Using CONSORT Evaluation [PDF]

open access: yes, 2015
Researchers have suggested that the advances of the Internet over the past two decades have gradually eliminated traditional offline methods of obtaining sexual material.
A Cooper   +64 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Violations of the right to food during deprivation of liberty: a global socio-legal assessment of United Nations Human Rights Treaty Bodies and the European Committee for the Prevention of Torture and Inhuman or Degrading Treatment or Punishment mission reporting on selected prisons since 2015

open access: yesBMC Public Health
Background States have a heightened duty of care owed to persons deprived of their liberty extending beyond the prohibition of torture and discrimination.
Marie Claire Van Hout   +3 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

“Everything is kind of the same except my mind is with me”: exploring cannabis substitution in a sample of adults in early recovery from an opioid or stimulant addiction

open access: yesHarm Reduction Journal
Background Recovery from addiction is frequently equated with abstinence. However, some individuals who resolve an addiction continue to use substances, including via substitution (i.e., increased use of one substance after eliminating/ reducing another).
Corinne A. Beaugard   +2 more
doaj   +1 more source

Work-Related Mental Health and Job Performance: Can Mindfulness Help? [PDF]

open access: yes, 2014
Work-related mental health issues such as work-related stress and addiction to work impose a significant health and economic burden to the employee, the employing organization, and the country of work more generally. Interventions that can be empirically
A Chiesa   +48 more
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

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