Results 71 to 80 of about 505,624 (288)

Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment [PDF]

open access: yes, 2015
Research into Internet addiction (IA) has grown rapidly over the last decade. The topic has generated a great deal of debate, particularly in relation to how IA can be defined conceptually as well as the many methodological limitations.
Griffiths, MD, Kuss, DJ, Pontes, HM
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multidimensional Work Addiction in Upper Secondary School Teachers

open access: yesMultidisciplinary Journal of School Education
Research Objectives and Problems: The aim of this research is to determine the level and structure of multidimensional work addiction among the surveyed secondary school teachers.
Katarzyna Nowosad
doaj   +1 more source

Work-Life Balance, Work Addiction and Job Satisfaction of Professional Social Workers in Kerala

open access: yesJournal of Social Work Education and Practice, 2023
Social work is a profession that aims to improve people's quality of life. The discipline focuses on assisting those experiencing difficulties and troubles in finding solutions and helping themselves.
Sona Francis, Cyril John, Selgin Joseph
doaj  

Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]

open access: yes, 2011
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter   +5 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Understanding Perceptions of Problematic Facebook Use: When People Experience Negative Life Impact and a Lack of Control

open access: yes, 2019
While many people use social network sites to connect with friends and family, some feel that their use is problematic, seriously affecting their sleep, work, or life.
Biolcati Roberta   +8 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Addiction to work and factors relating to this: a cross-sectional study on doctors in the state of Paraíba

open access: yesSão Paulo Medical Journal, 2017
CONTEXT AND OBJECTIVE: Addiction to work is one of the new behavioral phenomena present in organizations and it is characterized by excess work and compulsion to work.
Walter Fernandes Azevedo   +1 more
doaj   +1 more source

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