Results 111 to 120 of about 2,507,138 (268)
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Psychosocial work environment and health among ambulance clinicians in northern Sweden. [PDF]
Hedqvist AT +3 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Identifying Elements of a School Nurse's Work Environment That Are Salient to Their Job Outcomes: A Scoping Review. [PDF]
Heredia MR, Brom H, Lake ET, Lasater KB.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
The Association Between the Nursing Work Environment and Missed Nursing Care: A Systematic Review and Meta-Analysis. [PDF]
Mamić M +8 more
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
The Influence of Work Environment, Work Stress, and Work Discipline on Work Achievement
Success in building good governance in an agency is highly dependent on the support of quality human resources. The quality of human resources is directly proportional to the quality of work produced; the better the quality of human resources, the ...
Tri Mulyani Kartini +1 more
doaj
Development of the Japanese version of the work-life integration scale: Focusing on the work environment in Japan. [PDF]
Uchiyama A +6 more
europepmc +1 more source

