Results 61 to 70 of about 3,156,114 (316)

Study on the Combined Effect of Inclined Natural Fracture and Water Jet Slot on the Blast-Induced Crack Propagation Law

Shock and Vibration, 2022
For the purpose of uncovering the influence law on the explosion stress wave transmission and blast-induced crack propagation by inclined natural fracture and water jet slot, the influential mechanism for the transmission law of explosion stress wave due
Dengfeng Su, Zizheng Jia, Qiang Zhu, Zhengguo Li, Banghong Chen, Dandan Zheng, Renjun Tian   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Overtime work and its effects on sleep, sleepiness, cortisol and blood pressure in an experimental field study

, 2006
Objectives Previous studies of long workhours and their effects on stress, sleep, and health show inconclusive results. This inconclusiveness may be partly due to methodological problems such as the use of between-group designs or comparisons before and ...
Torbjörn Åkerstedt, Anna Dahlgren, Åkerstedt, Torbjörn, Göran Kecklund, Dahlgren, Anna, Kecklund, Göran   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health Behaviors and Overweight in Nursing Home Employees: Contribution of Workplace Stressors and Implications for Worksite Health Promotion

The Scientific World Journal, 2015
Background. Many worksite health promotion programs ignore the potential influence of working conditions on unhealthy behaviors. Methods. A study of nursing home employees (56% nursing aides) utilized a standardized questionnaire.
Helena Miranda, Rebecca J. Gore, Jon Boyer, Suzanne Nobrega, Laura Punnett   +4 more
doaj   +1 more source

Identification of needs of integrated approaches of occupational health and safety and health promotion [PDF]

Health Promotion Perspectives
Background: Occupational health and safety (OHS) interventions predominantly target workplace ergonomic, psychosocial, and material risks. Workplace health promotion (WHP) interventions have a primary focus on health education-related activities and ...
Yanming Lu, Nektarios Karanikas, Julie-Anne Carroll   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Interventions to reduce sedentary behavior and increase physical activity during productive work: a systematic review

, 2016
Objectives: Many current jobs are characterized by sedentary behaviour (SB) and lack of physical activity (PA). Interventions addressing SB and PA at the workplace may benefit workers’ health. The present review is the first to focus on the effectiveness
Koppes, Lando L.J.,, Koppes, Lando L. J., Srinivasan, Divya,, Koppes, Lando L.J., Hendriksen, Ingrid J.M.,, Commissaris, Dianne A. C. M., Mathiassen, Svend Erik, Hendriksen, Ingrid J.M., Huysmans, Maaike A.,, Hendriksen, Ingrid J. M., Srinivasan, Divya, Huysmans, Maaike A., Huijsmans, Maaike, Commissaris, Dianne A. C. M.,, Mathiassen, Svend Erik,   +14 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Avoiding the ‘McJobs’: unemployed job seekers and attitudes to service work

, 2004
Service employment plays an increasingly important role in the UK economy. However, it has been suggested that some forms of service work are unattractive for many unemployed job seekers, and particularly those formerly employed in ‘traditional’ sectors.
Lindsay, Colin, McQuaid, Ronald W., McQuaid, Ronald   +2 more
core   +1 more source