Results 61 to 70 of about 939,772 (261)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Serum parameters and energy balance during the Yukon Arctic Ultra: a multistage ultramarathon in Arctic conditions

open access: yesFrontiers in Nutrition
PurposeThe objective of this study is to focus on energy intake and expenditure, as well as changes in various serum parameters regarding stress and metabolism, during the Yukon Arctic Ultra (YAU), an ultramarathon of 690 km length, under Arctic ...
Adriane K. Schalt   +5 more
doaj   +1 more source

Comparison of harvester work in forest and simulator environments

open access: yesSilva Fennica, 2005
Harvester simulators offer a safe and cost-saving method for studying the basics of harvester controls and working technique. Therefore, harvester simulators are increasingly being used in the education of harvester operators.
Ovaskainen, Heikki
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Creativity-enhancing work environments: Eventisation through an inspiring work atmosphere in temporary proximity

open access: yesRaumforschung und Raumordnung, 2020
The objective of this paper is to understand how work processes and the quality of physical places support creative knowledge generation. The creation of knowledge is linked to both social space and physical place, and is influenced by steady socio ...
Madeleine Wagner, Anna Growe
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Collaborative work, a didactics to educate in rural environments

open access: yesSenderos Pedagogicos, 2010
In this paper, collaborative work contributions to teacher formation in rural sectors were corroborated, as well as relationships between primary education students’ textual production from Rural Educational Centers —CER— and Rural Educational ...
Elvia Patricia Arango Zuleta
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Competencies for leadership development in hybrid work environments

open access: yesSA Journal of Human Resource Management
Orientation: The exponential change experienced by organisations, driven by the Fourth Industrial Revolution (4IR) and accelerated by the coronavirus disease 2019 (COVID-19) pandemic, has transformed work arrangements and placed new demands on ...
Mmathema A.C. Matle, Karel Stanz
doaj   +1 more source

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