Results 81 to 90 of about 3,974,625 (304)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Informal Home Care in the Digital Transformation: Platform Design and Work Ethics of Care

Social Sciences
With the aging society in Germany, the demand for informal care in private households is rising. This has led to a growing market for digital platforms that broker informal care services.
Anna Katharina Korn
doaj   +1 more source

The Survey of the Gap between Existent Work Ethics and Oral work Ethics [PDF]

Muṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2014
Organizational ethics in hospitality industry is the most important challenge are facing to it players in this industry; as a matter of fact, hotels can make Competitive Advantage by use of ethics in their activities for themselves and/or fall in ...
Mir Ali Seyed Naghavi, Seyed Mohammad Mirtaghian Roudsari   +1 more
doaj  

Planning for the Discharge, not for Patient Self-Management at Home – An Observational and Interview Study of Hospital Discharge

International Journal of Integrated Care, 2017
Introduction and objective: Despite recent interest in care transitions, little is known about how patients are prepared for the self-management tasks following the hospitalization.
Maria Flink, Mirjam Ekstedt
doaj   +1 more source

Considering the public private-dichotomy: Hannah Arendt, Václav Havel and Victor Klemperer on the importance of the private [PDF]

, 2017
This paper examines the political significance of discursive activity in the private sphere in the thought of Hannah Arendt, Václav Havel, and Victor Klemperer.
Brennan, Daniel
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The work ethics of muslim woman Songket weavers in increasing family income: Sukarare tourism village, Indonesia. [PDF]

Heliyon, 2022
El Badriati B, Saleh M, Nahar FH, Aprilia TL, Azizurrohman M.   +4 more
europepmc   +1 more source

The Value of Consciousness [PDF]

, 2019
Recent work within such disparate research areas as the epistemology of perception, theories of well-being, animal and medical ethics, the philosophy of consciousness, and theories of understanding in philosophy of science and epistemology has featured ...
Kriegel, Uriah
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Islamic work ethics and employee’s task performance: The mediation role of affective commitment [PDF]

Problems and Perspectives in Management
The study investigates the effect of Islamic work ethics on task performance. Further, it examines the mediating role of affective commitment on the relationship between Islamic work ethics and task performance.
Ali Ateeq, Mohammed Alzoraiki, Marwan Milhem, Mujeeb Al-Absy, Ranyia Ateeq   +4 more
doaj   +1 more source