Results 81 to 90 of about 2,119,607 (304)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Students' perceptual change of professional ethics after engaging in work-integrated learning

open access: yes, 2014
When students undertake work placements, they become immersed in a relevant community of practice, where they are required to meet the social demands to perform within the norms of this community.
Campbell, Matthew   +2 more
core  

Planning for the Discharge, not for Patient Self-Management at Home – An Observational and Interview Study of Hospital Discharge

open access: yesInternational Journal of Integrated Care, 2017
Introduction and objective: Despite recent interest in care transitions, little is known about how patients are prepared for the self-management tasks following the hospitalization.
Maria Flink, Mirjam Ekstedt
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Ethics outside, within or beyond OR models [PDF]

open access: yes
Since ethical concerns are calling for more attention within Operational Research, we present three approaches to combine Operational Research models with ethics.
Luk N. Van Wassenhove, Marc Le Menestrel
core  

Spontaneous ethics in nurses’ willingness to work during a pandemic

open access: yes, 2022
Background: In modern healthcare, the role of solidarity, altruism and the natural response to moral challenges in life-threatening situations is still rather unexplored.
Slettmyr, Anna,   +6 more
core   +1 more source

Islamic work ethics and employee’s task performance: The mediation role of affective commitment [PDF]

open access: yesProblems and Perspectives in Management
The study investigates the effect of Islamic work ethics on task performance. Further, it examines the mediating role of affective commitment on the relationship between Islamic work ethics and task performance.
Ali Ateeq   +4 more
doaj   +1 more source

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