Results 71 to 80 of about 2,119,607 (304)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Transmission Towers: A case study for use in teaching in Engineering Ethics

, 2010
This is an Engineering Ethics case study from the IDEA CETL. It examines the moral issues surrounding a disagreement with a boss at work concerning the safety of a transmission tower. It considers safety and risk and whistleblowing.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds, Dr Heather Fotheringham   +1 more
core  

The Structural Relations of Work Ethics and Purposefulness in Life with the Students’ Spiritual Well-being: The Mediating Role of Work Engagement

مسائل کاربردی تعلیم و تربیت اسلامی, 2022
Objective The purpose of the present study was to investigate the structural relationships between work ethics (with an Islamic approach) and purposefulness in life with spiritual well-being through the mediation of work engagement.
Farzaneh Michaeli Manee, Sheler Abkhiz
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Noise at Work: A case study for use in teaching in Engineering Ethics

, 2010
This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the issues surrounding health and safety in the workplace in relation to noise pollution. It raises issues such as confidentiality; employer-employee relations; safety and
Jane Stone, Inter-Disciplinary Ethics Applied Cetl, University of Leeds, Sayeed Khan, Dr Heather Fotheringham   +3 more
core  

Informal Home Care in the Digital Transformation: Platform Design and Work Ethics of Care

Social Sciences
With the aging society in Germany, the demand for informal care in private households is rising. This has led to a growing market for digital platforms that broker informal care services.
Anna Katharina Korn
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

French Engineers: A case study for use in teaching in Engineering Ethics

, 2010
This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the problem of what to do when encountering unacceptable behaviour (drinking during work hours) while working abroad. It raises issues such as moral relativism; safety and
Inter-Disciplinary Ethics Applied Cetl, University of Leeds, Dr Heather Fotheringham   +1 more
core  

The Survey of the Gap between Existent Work Ethics and Oral work Ethics [PDF]

Muṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2014
Organizational ethics in hospitality industry is the most important challenge are facing to it players in this industry; as a matter of fact, hotels can make Competitive Advantage by use of ethics in their activities for themselves and/or fall in ...
Mir Ali Seyed Naghavi, Seyed Mohammad Mirtaghian Roudsari   +1 more
doaj  

The work ethics of muslim woman Songket weavers in increasing family income: Sukarare tourism village, Indonesia. [PDF]

Heliyon, 2022
El Badriati B, Saleh M, Nahar FH, Aprilia TL, Azizurrohman M.   +4 more
europepmc   +1 more source