Results 161 to 170 of about 12,447,623 (292)

Impact of mental and physical workload on work function in office workers with musculoskeletal disorders. [PDF]

BMC Musculoskelet Disord
Arefian S, Laybidi MI, Vahedi M, Melloh M, Mokhtarinia HR.   +4 more
europepmc   +1 more source

Cognitive impairments among patients in a long-COVID clinic: Prevalence, pattern and relation to illness severity, work function and quality of life. [PDF]

J Affect Disord, 2023
Miskowiak KW, Pedersen JK, Gunnarsson DV, Roikjer TK, Podlekareva D, Hansen H, Dall CH, Johnsen S.   +7 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Engineering Work Function to Stabilize Metal Oxides in Reactive Hydrogen. [PDF]

J Phys Chem Lett
Rehman A, van de Kruijs RWE, van den Beld WTE, Sturm JM, Ackermann M.   +4 more
europepmc   +1 more source

Effect of Step Gate Work Function on InGaAs p-TFET for Low Power Switching Applications. [PDF]

Nanomaterials (Basel), 2021
Azam SMT, Bakibillah ASM, Hasan MT, Kamal MAS.   +3 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Constructing a visible-light-excited Z-scheme heterojunction by engineering the directional N-C/Cu insertion layer: overcoming work function mismatches. [PDF]

Chem Sci
Gao H, He X, Li J, Zhu Q, Qin C, Sun L, Zhi S, Yang L, Zhan W, Zhao J, Han X.   +10 more
europepmc   +1 more source

Local stiffness and work function variations of hexagonal boron nitride on Cu(111). [PDF]

Beilstein J Nanotechnol, 2021
Grewal A, Wang Y, Münks M, Kern K, Ternes M.   +4 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Local work function on graphene nanoribbons. [PDF]

Beilstein J Nanotechnol
Rothhardt D, Kimouche A, Klamroth T, Hoffmann-Vogel R.   +3 more
europepmc   +1 more source