Results 91 to 100 of about 2,135,172 (241)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Myocardial Work Index in Professional Football Players: A Novel Method for Assessment of Cardiac Adaptation. [PDF]
J Clin Med, 2023 Refoyo E +8 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Agentes de limpeza terceirizados: entre o ressentimento e o reconhecimento
Revista Brasileira de Saúde OcupacionalResumo Objetivo: analisar a percepção sobre a atividade de trabalho dos agentes de limpeza terceirizados de uma faculdade pública e determinar seu índice de capacidade para o trabalho.
Sandra Francisca Bezerra Gemma +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Gender and work ability among public workers: a cross-sectional study
Online Brazilian Journal of Nursing, 2007 Objective: to assess demographic and lifestyles characteristics, working conditions and work ability among public workers looking at gender as a mediator factor. Methods: A cross-sectional study was carried out at a public health institution.
Maria Silvia Monteiro +3 more
doaj +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Validation of Psychometric Properties of the Nursing Work Index-Revised Scale in Portugal. [PDF]
Int J Environ Res Public Health, 2022 Anunciada S +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
ANNUAL FACULTY WORK ASSESSMENT BY USING THE INDEX SYSTEM
Высшее образование в России, 2016 . The article presents brief excerpts from the annual report of the supervisor of the evaluation system of the faculty activities. The author dwells on the description of the gradual continuous improvement of the evaluation system of teachers, the data ...
Konstantin V. Rochev
doaj