Results 181 to 190 of about 4,285,820 (314)

Time Management and Work-Life Balance: A New Academic Paradigm. [PDF]

Int J Prev Med
Sharma P, Chadha L, Kaur R, Arya I.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Improving work and life balance : building a multilevel model of work-life balance focusing on group structure and relational job design

, 2013
One in five Australian workers believes that work doesn’t fit well with their family and social commitments. Concurrently, organisations are recognising that to stay competitive they need policies and practices that support the multiple aspects of ...
Chang, Artemis, Bradley, Lisa M.
core  

Workplace Gaslighting: Implications for Employees' Mental Health and Work Life in Greece. [PDF]

Healthcare (Basel)
Moisoglou I, Katsiroumpa A, Konstantakopoulou O, Mangoulia P, Tsiachri M, Koinis A, Kyriakatis GM, Galanis P.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Psychological wellbeing in informal workers within the gig economy: the roles of social support, work-life balance, workload, and time pressure. [PDF]

Front Psychol
Pongsapan TI, Ramaditya M, Anjarwi AW.
europepmc   +1 more source

Work as Life, Life as Work: Rethinking the Limits of Work–Life Balance in the Twenty-First Century

This study argues that work and life are inseparable under late capitalism. By examining the quantity, intensity, and quality of  labour, it critiques the concept of “work–life balance” and reimagines work as a site of dignity, capability, and human flourishing.
openaire   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The Role of Burnout Dimensions, Job Stress, and Work-Life Balance in Multisite Musculoskeletal Pain Among Academicians in Türkiye: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Kayabınar E, Sağ Zİ, Kayabınar B, Atak E.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source