Results 71 to 80 of about 1,568,884 (267)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

“Morality Matters”: The Relative Impact of Moral Demands on Indicators of Wellbeing in Hospital Personnel

open access: yesSafety and Health at Work, 2022
Celine Baele   +3 more
doaj   +1 more source

The Impact of Quality of Work Organization on Distress and Absenteeism among Healthcare Workers. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Magnavita N   +3 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Fortified Construction Techniques in al-Ṭagr al-Awsaṯ, 8th–13th Centuries

open access: yesArts, 2018
Spanish Islamic military architecture shows an attempt at the systematization of works, techniques, and defensive elements, commencing in the era of the Umayyad Emirate and Caliphate up to the North African Empires (Almoravids and Almohads). This article
Ignacio Javier Gil Crespo   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The value of self-care during climate-related extreme weather events (EWE) to support sexual and reproductive health and rights

open access: yesGlobal Public Health
Climate-related extreme weather events (EWE) affect sexual and reproductive health and rights (SRHR) outcomes through complex and multi-level pathways. These include institutional-level effects on health systems, such as damaged health infrastructure and
Manjulaa Narasimhan   +3 more
doaj   +1 more source

Profesiones de servicio y digitalización: implicaciones y sugerencias para la concepción de procesos de formación

open access: yesLaboreal, 2018
In the services sector professions, digitalization is transforming the individual and collective activity and the relationship with the users. Though not exclusively, this aspect is particularly visible when digitalization refers to the management of the
Deli Salini   +3 more
doaj   +1 more source

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