Results 181 to 190 of about 16,598,865 (356)
Increased Women's Labour Force Participation in Europe: Progress in the Work-Life Balance or Polarization of Behaviours? [PDF]
Although the increase in female labour force participation is a fairly widespread trend, there is still a considerable diversity of situations across Europe from north to south. To identify the factors that may explain these differences, Olivier Thévenon
Olivier Thevenon
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Documenting Work: From Participant Observation to Participant Tracing
, 2019 This paper explores the methodological aspects of studying distributed work by focusing on the more tangible aspects of this work, namely documents. We show how 1) researchers should engage in an initial mapping of documents before starting to track them; 2) the ongoing flow of virtual organizing only becomes apparent by triangulating the digital flow ...
Østerlund, C +4 more
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Use and users of physiotherapy in an outpatient practice in primary health
Fysioterapeuten, 2014 Aim: To examine demographic variables, use of health services, expectation of physiotherapy efficiency, pain characteristics of patients in a physiotherapy out-patient practice in Norway, and to examine whether regular users of physiotherapy differ from ...
Gro Opseth +3 more
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Does previous sickness absence affect work participation after vocational labour market training? A difference-in-differences propensity score matching approach. [PDF]
Eur J Public Health, 2023 Salonen L +5 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source