Results 281 to 290 of about 16,598,865 (356)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Working Conditions in Mid-life and Participation in Voluntary Work After Labour Market Exit [PDF]

Siegrist, Johannes, Wahrendorf, Morten
core  

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Work participation, sensory processing and sleep quality in adults with attention-deficit hyperactive disorder

Work, 2022
BACKGROUND: Although studies have indicated significant effects of attention-deficit hyperactive disorder (ADHD) on work participation, the mechanism underlying work participation of adults with ADHD is still unclear.
N. Grinblat, S. Rosenblum
semanticscholar   +1 more source

Participation in Strategy Work

2015
Introduction This chapter examines participation in strategy research in general and in strategy-as-practice research in particular. Participation is arguably a key issue in strategy process research because it helps to create commitment to strategies, and its absence may have a negative impact on the quality of decision-making (Floyd and Wooldridge ...
Pikka-Maaria Laine, Eero Vaara
openaire   +5 more sources

Barriers and facilitators to work participation for persons with lower limb amputations in Bangladesh following prosthetic rehabilitation

Prosthetics and orthotics international, 2020
Background: Lower limb amputation due to workplace injury and motor vehicle accident is common in Bangladesh. Qualitative research may extend our understanding of how physical impairment and other factors, such as cultural norms, family roles and the ...
R. Stuckey, Pam Draganovic, M. M. Ullah, E. Fossey, M. Dillon   +4 more
semanticscholar   +1 more source