Results 171 to 180 of about 3,389,612 (313)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Work within organisational performance : proposals for an approach to study work performance

open access: yes, 2017
Cette thèse porte sur la performance du travail, c’est-à-dire sur la contribution du travail à la performance des organisations. Ce sujet a reçu peu d’attention dans la littérature, et s’articule autour de deux notions complexes : le travail et la performance.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Optimizing work performance and engagement in adults with hearing loss: the role of hearing devices. [PDF]

open access: yesSci Rep
Lim S   +10 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

High Performance Work Practices and Employee Voice: A Comparison of Japanese and Korean Workers [PDF]

open access: yes
Using a unique new cross-national survey of Japanese and Korean workers, we report the first systematic evidence on the effects on employee voice of High Performance Work Practices (HPWPs) from the two economies which are noted for the wide use of HPWPs.
Chuma, Hiroyuki   +4 more
core  

The Individual Work Performance Questionnaire: Psychometric Properties of the Italian Version. [PDF]

open access: yesEur J Investig Health Psychol Educ, 2023
Platania S   +3 more
europepmc   +1 more source

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