Results 41 to 50 of about 15,601,884 (244)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Developing tutorials for advanced physics students : processes and lessons learned [PDF]

, 2014
Supported by the University of Colorado and NSF-CCLI grant #1023028.When education researchers describe newly developed curricular materials, they typically concentrate on the research base behind their design, and the efficacy of the final products, but
Steven J. Pollock, Charles Baily, Baily, Charles, Pollock, Steven, Michael Dubson, Dubson, Michael, Baily, Charles; id_orcid   +6 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Refined characterization of student perspectives on quantum physics [PDF]

, 2010
The perspectives of introductory classical physics students can often negatively influence how those students later interpret quantum phenomena when taking an introductory course in modern physics.
Charles Baily, Baily, Charles, Finkelstein, Noah D., Noah D. Finkelstein, Baily, Charles; id_orcid   +4 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Development of quantum perspectives in modern physics [PDF]

, 2009
Introductory undergraduate courses in classical physics stress a perspective that can be characterized as realist; from this perspective, all physical properties of a classical system can be simultaneously specified and thus determined at all future ...
Charles Baily, Baily, Charles, Finkelstein, Noah D., Noah D. Finkelstein, Baily, Charles; id_orcid   +4 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Flavor physics in the quark sector [PDF]

, 2008
In the past decade, one of the major challenges of particle physics has been to gain an in-depth understanding of the role of quark flavor. In this time frame, measurements and the theoretical interpretation of their results have advanced tremendously. A
Smith, Christopher, Isidori, G, C. Tarantino, F. Martinez Vidal, Tonelli, D, Becher T, J. Laiho, Flynn, J. M., R. V. Kowalewski, Maltman, K, G. Eigen, Smith, C., F. Harr, R., Gambino P., R Faccini (16065512), Passemar, Emilie, Powell A., Asner, David Mark, Cabibbo N., Jüttner, A, P. Krokovny, Goto, Toru, Sozzi, M., Scholz EE, Schwartz, Alan Jay, Bona M., Kronfeld AS, M. Palutan, Coleman J. P., Libby, J, Antonelli M, Rotondo M, L. Silvestrini, Schneider, O., Martinez-Vidal, F., Bozzi, C., Libby J., Gershon T. J., Smith C., buras, A., N. Cabibbo, T. Goto, Dalseno, JP, Sacco, Roberto, Soni A, Bloise, C., C.H. Davies, Dungel W., S. van de Water, R., Simula, S., Westhoff S., petrov, A., Paradisi, Paride, A. J. Schwartz, Masiero A., Westhoff, Susanne, Dingfelder, J., P. Koppenburg, J. Marciano, W., A.V. Telnov, V. Telnov, A., Lopes Pegn, D, harr, R., Antonelli, M, Antonelli, Mario, T. E. Latham, Towner I. S., D. P. Cronin Hennessy, Bevan, A, Tantalo N., Flynn, J.M., Lunghi E, Rotondo, M, M. Moulson, kowalewski, R., T.J. Gershon, Prell, Soeren Andre, Gambino, P, Isidori G., Prell, S., Coleman, J. P., Feldmann, T., Towner, Ian S., Lubicz, V., Buras, A.J., Schumm BA, Coleman, J.P., Bozzi, C, Cabibbo, N, A.H. Hoang, Mohanty, G., Brod, J., Tantalo, N, Libby, J., Carbone A, M. Wingate, Tonelli D., Masiero, A., Di Lodovico, Francesca, R. F. Harr, Brod, J, Parsa Z., Becher, Thomas, Sozzi M, Martin, E. C., Towner, I. S., Buras, AJ, Hoang, André, Dalseno, J. P, J. Libby, Brod J., Gambino, Paolo, latham, T., Tonelli D, jaffe, D., Stocchi, A., Bondar, Alexander E., Spradlin P., Grojean, Christophe, Spradlin P, Lu, C. D, Di Lodovico F., M. Rotondo, Lueth V. G., Pecjak, B.D., Mescia F., DiLodovico, F, Simonetto, F., Kronfeld, A.S., Plaster, B, Jager, Sebastian, Lu, C.D, Schumm, B.A, Dingfelder J., A. Sibidanov, P. Urquijo, A.J. Bevan, Harr, R.F, Doležal, Z., Rescigno, M, Bevan A. J., V. Cirigliano, Marciano, W.J, Sonnenschein, Lars, Simonetto, Franco, A. J. Buras, Dingfelder, J, Lunghi, Enrico, K. Furic, I., Donati, S., Patel, M., Wingate M., SOZZI, MARCO STANISLAO, Tantalo, N., C. Schwanda, O. Schneider, Dalseno, J.P, Giagu S, V. G. Luth, Golowich, E., Xie, Y, hoang, A., H. Hoang, A., Rotondo M., E. Jaffe, D., Mohanty, G. B., Scholz, E. E, Koppenburg, P, J. Zupan, Soni, A., Trabelsi, K, Petrov A. A., Shipsey IJ, Koppenburg, Patrick Stefan, Trabelsi K., Martinez-Vidal F, F. Ferroni, Parsa, Zohreh, flynn, J., Schneider O, Khodjamirian, A., J. Rademaker, Moulson, M., Brod, Joachim, Harr, R. F, Golowich, Eugene, Hoang A. H., Haisch, U.A., Coleman, JP, Palutan M, Bona, M, Nishid. S, Masiero A, Faccini, R., I.S. Towner, H. Neufeld, Lubicz, Vittorio, Bozzi, Concezio, Buras, A, Jaffe, D.E, Kronfeld, A. S., S. Westhoff, Schumm, Bruce Andrew, Lu, C. D., Schilling, C.J, A. Powell, Ricciardi, Stefania, Kowalewski, R.V, G. Mohanty, Zupan, J., Bevan AJ, Telnov, AV, Spadaro, T, Antonelli, M., Sonnenschein L., Asner, DM, luth, V., Bloise C., J.P. Coleman, Egede, U., Fernando Ferroni, Y. Xie, Shipsey, I.J, Isidori G, Franco, Enrico, E. Scholz, E., Sonnenschein, L, Van de Water, R.S., Grojean C., Sciascia, Barbara, J. van Kooten, R., Bona, M., Di Lodovico F, Tarantino, Cecilia, Rescigno M., Zupan J, Maltman K., D. E. Jaffe, Volpi, Guido, Wingate, M, Mohanty G, Gardi E, E. E. Scholz, Bondar, A., Martin, Emilie Claire Mutsumi, Harr, Robert Francis, Shigemitsu, J, Gershon, T.J., Scholz, E.E, Cronin-Hennessy DP, N.i.s.h.i.d. S, Schilling, C. J, Lunghi, E, Powell, A., Plaster B., G. Isidori, Eigen G, Egede U., Offen, N, Franco, E., F. Martinez-Vidal, H. Davies, C., Schneider, O, Feldmann, T, E. Golowich, Pich, A., Martin, E. C, Plaster, Brad, Bauer, Daniel Adams, Moulson M, M. Patel, E. Latham, T., S. Jager, Martinez Vidal F, S. Nishida, Schwartz, A.J., Latham TE, G. Lanfranchi, Virto, J., Schwanda, C., Sacco, R., Pierini M, Flynn, J. M, Nishida, S., Jaffe D. E., Eigen, G, Neufeld H, Martinelli G, Van Kooten, Richard J., Palutan, M., Hurth, Tobias, Shigemitsu J., Petrov, A.A., G. Lüth, V., Offen N., Di Lodovico, F, Juettner, A., Davies CH, Koppenburg P, Prell S, Guadagnoli D., Rotondo, Marcello, Neufeld H., Nishida, Shohei, M. Pierini, Robbe P., Latham, T. E., R.J. Van Kooten, Khodjamirian A, M. Flynn, J., Van Kooten, R.J., Sciasci, B, Wilkinson G, Lopes Pegna, D., Gambino, P., Lüth, V.G, A. Pich, Moulson M., C. D. Lu, Spadaro T., Flynn J. M., Petrov, A.A, Laiho J., Latham T. E., C. Grojean, Dungel W, Dalseno J. P., A. A. Petrov, Golowich, E, Laiho, J, Furic, I. K., T. Hurth, Schumm, B. A, Telnov, Alexandre V., Donati S, Spradlin, Patrick Michael, Cavoto, Gianluca, U.A. Haisch, Sibidanov, A., Spadaro, T., Jaffe, D.E., Franco E, Lunghi E., Telnov, A.V., Bevan, A.J., Bon, M, Nishida S, Cronin-Hennessy, D.P, Moulson, M, Soni, A, Serrano, Justine, Hoang AH, Eigen G., Xie Y., Greub C, Juttner, Andreas, Hurth, T., Feldmann T., R. Wanke, Hoang, A. H, S. Simula, Cabibbo, N., Kronfeld, A. S, Haisch, U.A, Pich Zardoya, Antonio, Martin EC, Rademaker J, J. P. Dalseno, Urquijo P, Paradisi, P., Kronfeld, Andreas Samuel, Bloise C, Furic IK, Schilling CJ, Luth, V. G., Greub, C., Dingfelder J, Kowalewski, R. V, Lu, Cai-Dian, T. Becher, Schneider, Olivier, Towner, I.S, Z. Parsa, Bevan, AJ, Antonelli M., Offen, N., Spradlin, P., Smith, C, Powell, A, Juttner, A., Pegna D. Lopes, bevan, A., J.M. Flynn, Pegna DL, Coleman JP, Harr, R. F., M. Asner, D., Wingate, M., Prell S., Bona, Marcella, D. M. Asner, Sordini, Viola, D. Lopes Pegna, Furić, I.K, Simonetto, F, Wilkinson, G., Donati, Simone, U. A. Haisch, Robbe, P., J. Shipsey, I., Franco, E, P. Paradisi, K. Trabelsi, Shigemitsu J, Lueth VG, E. Passemar, S. Prell, Goto T, R. Faccini, Mohanty, Gagan Bihari, Tarantino, C., Towner IS, Davies C. H., E.E. Scholz, Grojean, C., Xie Y, Guadagnoli D, Rescigno M, Haisch, U. A., Blanke, M, Martinez-Vidal, F, Furic I. K., Bozzi C., Latham, T. E, Schneider O., Libby J, Buras, A. J., davies, C., Schwanda C, Tantalo, Nazario, W.J. Marciano, Franco E., Isidori, Gino, Pars, Z, Petrov AA, Isidori, G., Cronin Hennessy DP, Pich A., J. M. Flynn, G. Cavoto, Tarantino, C, Krokovny P, Marciano, W. J., Blanke M., Giagu, Stefano, J. P. Coleman, M. Fujikawa, D. Lu, C., Jaeger, S., Marciano, William J., J. Gershon, T., Simul, S, Stocchi A., S. Kronfeld, A., Paradisi P, Cronin-Hennessy, D.P., I. S. Towner, D. Guadagnoli, Wanke, R., Passemar, E, Cirigliano, V, Gardi, E, B. Sciascia, Lanfranchi, G., Cronin-Hennessy, D. P., V. Lubicz, E. Franco, C. J. Schilling, Bondar A, S. Ricciardi, Dalseno, J. P., Rodrigues E, Faccini, Riccardo, C.J. Schilling, Pierini, M, A. Carbone, Rademaker, J., G. Wilkinson, Serrano J, Krokovny P., kronfeld, A., Giagu, S, Stocchi, Achille, Neubert M., Hoang, A.H., R.F. Harr, Urquijo, Phillip, Paradisi, P, Prell, S, Virto, Javier, I. K. Furi¢, Blanke, M., Gambino P, Maltman K, Spadaro, Tommaso, V. Mateu, Davies, C.H, Rescigno, Marco, Telnov AV, Sacco R., Hurth T., Simula, Silvano, D. Bauer, Kowalewski, R. V., Neubert, M, Kronfeld A. S., scholz, E., J. Shigemitsu, Golowich E, Schilling C. J., F. Mescia, Neubert, Matthias, Scholz, E. E., Simonetto F, Pich, A, Pecjak BD, Silvestrini, L, Van Kooten RJ, Martin, E.C, Fujikawa M., Rodrigues, E., Davies, C. H, A. Juttner, Egede, Ulrik, Sibidanov, A, Pegna, D. Lopes, Sordini V., I. K. Furic, Westhoff, S., Plaster, B., Pich, Antonio, Gardi E., N. Offen, schilling, C., R. J. Van Kooten, A.A. Petrov, C. Greub, D.E. Jaffe, S. Giagu, Laiho, Jack, furic, I., Marciano, W.J., Ciuchini, M., DiLodovico, F., Rescigno, M., Silvestrini L, dalseno, J., Dalseno JP, Passemar E, Krokovny, P, Wanke R., et al (16046813), Rotondo, M., Schwartz, A. J., Mateu, V, Jaffe DE, Schwand, C, M. Rescigno, martin, E., Mateu, V., Latham, Thomas Edward, P. Robbe, L. Sonnenschein, T. Spadaro, Lubicz, V, Asner, David, Ricciardi, S, Sibidanov A, Neufeld, Helmut, W. Dungel, Silvestrini L., Parsa Z, Simonetto F., Cirigliano, Vincenzo, Ciuchini, M, R. Sacco, Bevan, Adrian John, Bauer D, F. Di Lodovico, A. H. Hoang, Schilling, C. J., A.S. Kronfeld, Bozzi C, Lanfranchi G, Moulson, Matthew, Buras A. J., Sacco, R, G. Volpi, shipsey, I., Hurth, T, Asner DM, Dolezal Z, Simula S, Pecjak, B. D., Schilling, C.J., Dingfelder, J. C., Pegna, D. L., Pierini, Maurizio, Bondar, A, Coleman, J. P, Asner, D. M, C.D. Lu, Passemar, E., Mesci, F, Luth, Vera G., K. Maltman, Tonelli, Diego, A. Schumm, B., E. Gardi, P. Coleman, J., J. Brod, Sordini, V, Dolezal, Zdenek, Telnov, A. V., Van de Water, R.S, Golowich E., Becher, T., Grojean C, Laiho J, Coleman, Jonathon P., Donati S., Gershon, T. J, Dolezal, Z, Wilkinson, G, Neufeld, H, T. Feldmann, Towner, I.S., D. Tonelli, Luth VG, E.C. Martin, Jaffe, D. E, Ferroni, F, Neubert, M., Sciascia, B., TANTALO, NAZZARIO, Guadagnoli, D., Feldmann T, Pecjak, B. D, Egede U, Kowalewski R. V., D.M. Asner, Neubert M, Kowalewski RV, Lu C. D., D.P. Cronin-Hennessy, Shipsey, I. J, Lu, C.D., Kowalewski, R.V., Khodjamirian, Alexander, Maltman, K., Egede, U, Haisch, U. A, Gershon, T.J, Cabibbo N, A. Masiero, Kronfeld, A.S, Palutan, M, C. Bloise, Fujikawa, M., Blanke M, Virto, J, Ferroni, Fernando, Limosani A, Robbe, P, Lopes Pegna, David, Virto J., Shipsey, I. J., Jaeger S., Martinelli, G., Serrano, J, M. Beneke, Trabelsi, K., Schwartz A. J., Pierini M., Neufeld, H., J. Schilling, C., Marciano WJ, Martinelli, G, Nishida S., Schumm, B. A., Eigen, Gerald, gershon, T., Cronin Hennessy D. P., Zupan J., A. Petrov, A., schwartz, A., Simula S., Khodjamirian, A, Feldmann, Thorsten, Ferroni F., Libby, James F., Serrano J., Goto, T., Gershon TJ, Patel M., M. Antonelli, Gershon, T. J., Jager, S., marciano, W., Faccini, R, Sozzi M., Buras, Andrzej J., coleman, J., Z. Dolezal, J.P. Dalseno, Silvestrini, L., Furić, I. K, Goto T., Sciascia B, Blanke, Monika, A. S. Kronfeld, Sordini V, Wanke R, Sozzi, Marco S., Van de Water R. S., Ciuchini M., Haisch UA, Soni A., Jaeger S, Sonnenschein L, Sozzi, M, Koppenburg, P., Bona M, Patel, M, Smith C, Martinelli G., Gardi, E., pecjak, B., Flynn, Jonathan M., Ricciardi S., Scholz, E.E., Harr, R.F., Harr R. F., Petrov, A. A., Hoang, A. H., Ferroni F, Guadagnoli, D, Sibidanov A., Wilkinson G., Soni, Amarjit, Van Kooten, R. J., E. C. Martin, Tarantino C, Zupan, Jure, Rademaker, J, Becher T., Tonelli, D., Sciascia B., Patel M, Robbe, Patrick, A. J. Bevan, Rademaker J., van de water, R., Martinez Vidal, F, Martínez-Vidal, Fernando, Wingate M, I. J. Shipsey, Mohanty, G, Bauer D., Brod J, Mescia F, Juettner A, Beneke M., C. Bozzi, A.J. Buras, Donati, S, T.E. Latham, Jaffe, D. E., Bondar A., R.V. Kowalewski, Trabelsi, Karim, Mohanty G., E. Rodrigues, Cronin-Hennessy, Daniel P., Cavoto, G., A. Bondar, V. Sordini, Pierini, M., Stocchi A, Jäger, S, Latham, T.E, Lüth, V. G, J. Serrano, Coleman, J.P, B. D. Pecjak, Van Kooten, R.J, Harr RF, Lu CD, Dalseno, J.P., Shipsey, I.J., Flynn JM, Bloise, C, Ricciardi, S., Robbe P, Marciano, William Joseph, telnov, A., Petrov, A. A, Martin, E.C., Beneke, M, R. S. Van De Water, Asner, D. M., Schwartz AJ, Dungel, W., Lanfranchi G., C. H. Davies, Jager S, Offen N, Buras AJ, Juttner A, J. Bevan, A., U. Egede, Pecjak, B.D, A. Khodjamirian, Khodjamirian A., Offen, Nils, Faccini R., G. Martinelli, A. V. Telnov, Volpi, G., Becher, Thomas G., J. Schwartz, A., A. Stocchi, Pich A, V. Kowalewski, R., B.A. Schumm, Davies, C. H., Kowalewski, Robert V., Palutan M., Tantalo N, M. Sozzi, Greub C., Silvestrini, Luca, Van de Water, R. S., Lueth, V. G., Cavoto G, CARBONE, ANGELO, Cirigliano V., Schwanda C., Shipsey, Ian P.J., Gershon, Timothy John, Beneke, Martin, Schumm, B.A., Marciano W. J., W. J. Marciano, A. Limosani, Grojean, C, I.J. Shipsey, Sonnenschein, L., Cirigliano, V., Limosani A., Carbone, A, Mescia, F., Spradlin, P, Sebastian Jaeger (4462564), Hurth T, Haisch U. A., Lunghi, E., Fujikaw, M, Martin E. C., Koppenburg P., Lanfranchi, G, Martinelli, Guido, towner, I., Shipsey I. J., Davies, CH, M. Neubert, Wingate, Matthew Bowen, Serrano, J., Wanke, R, Telnov A. V., Petrov, Alexey A., Juettner A., Van Kooten R. J., Sibidanov, A.L., N. Tantalo, Scholz, Enno E., Plaster B, lu, C., P. Spradlin, Latham, T.E., Sacco R, Schumm B. A., Urquijo P., E. Lunghi, Bevan, A. J., Giagu S., Giagu, S., Goto, T, Xie, Y., Cronin Hennessy, D. P, Stocchi, A, Laiho, J., Becher, T, Paradisi P., B. Plaster, Beneke M, Asner, D.M, Di Lodovico, F., Westhoff S, haisch, U., J. Virto, Powell A, Passemar E., Martinez Vidal F., cronin-hennessy, D., D. Pecjak, B., J. Dingfelder, Mescia, Federico, Masiero, A, Schwartz, A.J, Scholz E. E., Towner, I. S, Asner D. M., C. Smith, Schilling, Christopher James, Bauer, D., Virto J, Volpi G., Mateu V., Cavoto G., Krokovny, P., T. J. Gershon, Schwartz, A. J, Parsa, Z., Rodrigues, E, Ciuchini, Marco, Carbone, A., Mateu V, Westhoff, S, Guadagnoli, Diego, Carbone A., Gardi, E.; id_orcid, Faccini R, A.J. Schwartz, Rodrigues E., Fujikawa M, Ciuchini M, Spadaro T, Furic, Ivan K., Beneke, M., Hoang, Andre H., Urquijo, P, M. Blanke, Hoang, A.H, B. A. Schumm, Van Kooten, R. J, Eigen, G., Ricciardi S, Trabelsi K, Shigemitsu, J., Riccardo Faccini, Cirigliano V, Van de Water, Ruth S., A. Soni, C. Martin, E., Van de Water RS, P. Dalseno, J., Urquijo, P., Limosani, A, M. Bona, Flynn, J.M, Stefano Giagu, van kooten, R., P. Gambino, Lüth, V.G., S. Towner, I., Greub, C, Marciano, W. J, F. Simonetto, Lubicz V, Davies, C.H., S. Donati, Ferroni, F., schumm, B., Asner, D.M., B.D. Pecjak, Dolezal Z., Martínez Vidal, Fernando, Sordini, V., Cronin-Hennessy, DP, Dingfelder, Jochen C., Van de Water, R. S, Powell, Brian Alfred, Limosani, A., Bauer, D, Volpi, G, Dungel, W, Volpi G, Cavoto, G, Pecjak B. D.   +999 more
core   +1 more source