Results 181 to 190 of about 295,991 (236)

Patient-Reported Psychosocial Burdens and Quality of Life and Work Productivity Impacts Among Patients with Clinically Distinct Alopecia Areata Severity Profiles. [PDF]

Adv Ther
Hanson KA, Austin J, Clayton N, Anderson P, Vano-Galvan S, Marwaha S, Kurosky SK, Lejeune A, Piercy J, Law EH.   +9 more
europepmc   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Impact of chronic constipation symptoms on work productivity and daily activity: A large-scale internet survey. [PDF]

JGH Open
Ota T, Kuratani S, Masaki H, Ishizaki S, Seki H, Takebe T.   +5 more
europepmc   +1 more source

Gas Sensing With Aerogels: A Critical Review on Structure‐Property Correlations and Performance Optimization

Advanced Science, EarlyView.
With high specific surface area, and adjustable interface, aerogel provides a multi‐functional platform for gas sensing. This review systematically links structural parameters (specific surface area, pore size, heterojunctions) to sensing metrics (sensitivity, selectivity, stability), critically evaluates optimization strategies, and outlines future ...
Hao Guo, Linheng He, Qinxin Wang, Man Yuan, Shoutian Qiu, Wei Liu, Sheng Cui   +6 more
wiley   +1 more source

Associations Between Cognitive Impairment, Depressive Symptoms, and Work Productivity Loss in Patients With Bipolar Disorder: A Cross-Sectional Analysis. [PDF]

Neuropsychopharmacol Rep
Takaesu Y, Shiroma A, Nosaka T, Maruyama H.   +3 more
europepmc   +1 more source

Thermally Assisted Photocatalytic Dehydrogenation of Methanol in Continuous Steady‐State Operation

Advanced Science, EarlyView.
Thermally assisted photocatalytic methanol dehydrogenation on Pt/TiO2 enables formaldehyde and hydrogen production far beyond thermodynamic limits. Continuous operation delivers up to 95% selectivity over 70 h, and oxygen microdosing strongly boosts conversion by regenerating surface oxygen sites.
Stubenrauch Florian, Nathrath Phillip, Schörner Markus, Mahayni Yazan, Fritsch Birk, Hutzler Andreas, Wasserscheid Peter, Bösmann Andreas, Schühle Patrick   +8 more
wiley   +1 more source

Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after 2 years? [PDF]

Rheumatology (Oxford)
Bento da Silva A, Ramiro S, Boel A, van Lunteren M, Marques ML, van de Sande M, Fongen C, Exarchou S, Ramonda R, van der Heijde D, van Gaalen F.   +10 more
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Impact of Chronic Musculoskeletal Pain on Autonomic Function, Work Productivity, and Mood During Working Hours: A Pilot Cross-Sectional Study on IT Desk Workers. [PDF]

Cureus
Oka Y, Jiroumaru T, Hyodo Y, Kuroda M, Murata R, Fujikawa T.   +5 more
europepmc   +1 more source