Results 31 to 40 of about 292,818 (254)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Dandelion Program Generic Project Management Plan [PDF]

open access: yes, 2016
[Excerpt] There are significant benefits to clients in establishing an arrangement with Hewlett Packard Enterprise (HPE)/ Specialist People to access and acquire critical, skilled ICT resources by harnessing the talents and developing the skills of a ...
DXC Technology
core   +1 more source

Risk of injury after evening and night work – findings from the Danish Working Hour Database

open access: yesScandinavian Journal of Work, Environment & Health, 2018
OBJECTIVES: Evening and night work have been associated with higher risk of injury than day work. However, previous findings may be affected by recall bias and unmeasured confounding from differences between day, evening and night workers.
Helena B Nielsen   +9 more
doaj   +1 more source

Association between long working hours and unmet dental needs in wage workers

open access: yesBMC Oral Health, 2023
Background Many previous studies on the reasons behind unmet dental needs focus on economic issues. However, in this research, we aimed to investigate the relationship between long working hours and unmet dental needs while considering the influence of ...
Youngjin Choi, Inah Kim, Jaechul Song
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Optimal Portfolio Management in Alaska: A Case Study on Risk Characteristics of Environmental Consulting Companies [PDF]

open access: yes, 2016
A Project Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE in Project ManagementSharp declines in global oil prices have led to a marked contraction in Alaska’s natural resource dependent economy.
Willingham, Katura
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

MaLeS: A Framework for Automatic Tuning of Automated Theorem Provers

open access: yes, 2014
MaLeS is an automatic tuning framework for automated theorem provers. It provides solutions for both the strategy finding as well as the strategy scheduling problem.
Kühlwein, Daniel, Urban, Josef
core   +2 more sources

A Survey of 802.15.4 TSCH Schedulers for a Standardized Industrial Internet of Things

open access: yesSensors, 2021
Concepts such as Industry 4.0 and Cyber-Physical Systems may bring forward a new industrial revolution. These concepts require extensive connectivity far beyond what is provided by traditional industrial networks. The Industrial Internet of Things (IIoT)
Andreas Ramstad Urke   +2 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

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