Results 121 to 130 of about 23,609,372 (344)
, 1958 Perhaps the chief achievement of the Enlightenment was the creation of the social sciences and the application of these sciences to the problems of human existence.
Bloom, Robert L. +6 more
core
Evaluation of the NAS-ILAB Matrix for Monitoring International Labor Standards: Project Report [PDF]
, 2009 The Bureau of International Labor Affairs (ILAB) engaged the National Research Council of the National Academy of Sciences (NAS) to recommend a method to monitor and evaluate labor conditions in a given country.
Root, Lawrence S., Vernon, Ada A.
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BMC Digital HealthBackground Approximately 25% of adults in the United States aged 60 years and older experience Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD) which may be precursors to Alzheimer’s Disease.
Michael J. McCarthy +7 more
doaj +1 more source
Situating multimodal learning analytics [PDF]
, 2016 The digital age has introduced a host of new challenges and opportunities for the learning sciences community. These challenges and opportunities are particularly abundant in multimodal learning analytics (MMLA), a research methodology that aims to ...
Abrahamson, D +5 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Stress Among Health Care Professionals - The Need for Resiliency [PDF]
, 2011 Healthcare professionals are subjected to considerable levels of stress such as work overload, excessive working hours, sleep deprivation, repeated exposure to emotionally charged situations, dealing with difficult patients and conflicts with other ...
Kakunje, Anil
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Solving reaction-diffusion equations 10 times faster [PDF]
, 2003 The most popular numerical method for solving systems of reaction-diffusion equations continues to be a low order finite-difference scheme coupled with low order Euler time stepping.
Kassam, Aly-Khan
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